Vision REU Week 3. Image registration  Used mutual information-based registration from ITK Ben SchoepkeREU Week 36/8/07 Fixed imageMoving image Pre-registrationPost-registration.

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Presentation transcript:

Vision REU Week 3

Image registration  Used mutual information-based registration from ITK Ben SchoepkeREU Week 36/8/07 Fixed imageMoving image Pre-registrationPost-registration

Segmentation  Edema is arbitrarily shaped Ben SchoepkeREU Week 36/8/07

Mean shift segmentation  Need non-parametric segmentation: mean shift! Ben SchoepkeREU Week 36/8/07 Comaniciu, D., Meer, P.: Mean shift: A robust approach toward feature space analysis. IEEE Trans. Pattern Anal. Mach. Intell. 24(5) (2002) 603–619

Experimentation  Register images to T1 > Segment with mean shift > Compare Ben SchoepkeREU Week 36/8/07 T1T1e FLAIRT2 Ground truth edema estimate (un-segmented FLAIR image)

Experimentation results  Observed that edema is visible in FLAIR and T2, not visible in T1 and T1E  Run each segmented image through high pass filter  Edema segmented image = (FLAIR && T2) && !(T1 && T1E)  Problem: very sensitive to threshold selection Ben SchoepkeREU Week 36/8/07 Ground truth edema estimateResult

Next week  Use brain atlas to remove false positives  Probability of observing edema in CSF regions is ~0  Perform region-based analysis rather than pixel-by-pixel  Continue developing algorithm  Which modalities to use?  Test different slices  Merge with tumor segmentation code  3D segmentation Ben SchoepkeREU Week 36/8/07 Probabilistic brain atlas. Non-CSF is blue. Source: Leach et al.