0. Courses  Other Information 1.The Molecules of Life 2.The Origin of Life 3.The Cell – an Introduction 0. Courses  Other Information 1.The Molecules of Life 2.The Origin of Life 3.The Cell – an Introduction Content

Our courses Compulsory course: Elective courses: Cell Biology and Molecular Genetics Basics of Molecular Biology Frontiers of Molecular Biology Genetic Analysis Medical Molecular Biology and Genomics Developmental Genetics Pre-Med Department of Medical Biology Department of Medical Biology

Lecturers Zsolt Boldogkői Ernő Duda István Belecz János Szabad Dóra Tombácz Cell Biology and Molecular Genetics

Curriculum: 1. PowerPoint pictures + supplementary material (Word documents) – from our homepage 2. Textbook: LIFE (9th Edition) - 2 hours/week, 4 credit points - Time: every Tuesday 11:00 – 12:30 - Place: Ophthalmology Clinic (here) Cell Biology and Molecular Genetics

1. Origin of Life  Basics of Cell Biology 2. The DNA 3. RNAs  Proteins 4. Cell Cycle, Cytoskeleton  Cytogenetics 5. Transport Processes 6. Human Genome 7. Inheritance 8. Genetic Regulation  Epigenetics 10. Evolution 9. Genes and traits 11. Viruses 12. Bacteria 13. Techniques of Molecular and Cell Biology 14. Selected Topics in Biology 15. Basics of Cell Communication 16. Complex Cell Signaling Pathways * 17. Neural Communication 18. Genetic Regulation of Development 19. Immunogenetics 20. Genes and Behavior 21. Biotechnology  Recombinant Gene Technology 22. Frontiers of Molecular Biology 23.Molecular Biology of Cancer 24. Chromosomal Disorders 25. Molecular Biology of Diseases 26. Molecular Biology of Brain and Mental Disorders 27.Molecular – and Stem Cell Therapy 28.Medical Genomics Ist Semester 2nd Semester

Evolution Optional topic instead of Evolution: Cellular Energetics Evolution Optional topic instead of Evolution: Cellular Energetics

Test questions on each lecture: bonus points! Cell Biology and Molecular Genetics Cheating will be punished!

Three levels (1) Basic requirements maximal grade: 3 (2) Extra requirements: grades from 1 to 5 (3) Facultative requirements: will be not asked at the MTOs and the exams (1) Basic requirements maximal grade: 3 (2) Extra requirements: grades from 1 to 5 (3) Facultative requirements: will be not asked at the MTOs and the exams Curriculum Cell Biology and Molecular Genetics

EXAM: Written, but oral is also possible : Write an for the oral exam: MTOs 1 st MTO: Oct 17 – lectures practices 2 nd MTO: Nov lectures practices Retake MTO: Dec 9 Super Monday QUESTIONSmax. 100 points Essay questions: From basic requirements 3 questions = 60 points From Extra requirements 2 questions = 20 points Definitions : From basic requirements 5 questions: 5x2 p = 10 points From Extra requirements 5 questions: 5x2 p = 10 points QUESTIONSmax. 100 points Essay questions: From basic requirements 3 questions = 60 points From Extra requirements 2 questions = 20 points Definitions : From basic requirements 5 questions: 5x2 p = 10 points From Extra requirements 5 questions: 5x2 p = 10 points (1) The weeks before the MTOs (2) On Super Monday (December 9.) morning (1) The weeks before the MTOs (2) On Super Monday (December 9.) morning Consultations: Cell Biology and Molecular Genetics

Points and grades: MTO:EXAM: p: p:1 30,5 – 55p:245,5 – 63p:2 55,5 – 70p:363,5 – 75p:3 70,5 – 85p:475,5 – 90p:4 85,5-100p:590,5-100p:5 Points and grades: MTO:EXAM: p: p:1 30,5 – 55p:245,5 – 63p:2 55,5 – 70p:363,5 – 75p:3 70,5 – 85p:475,5 – 90p:4 85,5-100p:590,5-100p:5 Cell Biology and Molecular Genetics

(1) attendance of the lectures (2) attention in the lectures (3)Attendance and attention at the practices (4) activity in practices, seminars and lectures (5) good performance at the MTOs (6)Others: attendance in -Basics in Molecular Biology course -some Frontiers of Molecular Biology lectures (1) attendance of the lectures (2) attention in the lectures (3)Attendance and attention at the practices (4) activity in practices, seminars and lectures (5) good performance at the MTOs (6)Others: attendance in -Basics in Molecular Biology course -some Frontiers of Molecular Biology lectures Penalty: (1) failed the MTO(s) (2) non-attendance of practices Penalty: (1) failed the MTO(s) (2) non-attendance of practices Rewards: (bonus points and other premiums) Cell Biology and Molecular Genetics The MTO grades can be calculated to the exam grade

1 absence:nothing to do 2 absences: Report about the missing practices 3 absences : additional practical question on the exam 4-7 absences : no signiture in the index book 1 absence:nothing to do 2 absences: Report about the missing practices 3 absences : additional practical question on the exam 4-7 absences : no signiture in the index book Seprényi György Place: Department of Medical Biology 4 hrs/2 weeks, The first parts os the practices are seminars (2 groups are together at the larger practice hall!) Absences from the practices: Tests at the first 10 minutes of the practices: 5 questions (simple choice: 2-2 questions from the former two lectures and one question from the former practice) – Bonus points for the corrects answers practice Cell Biology and Molecular Genetics

1. Handling of technical instruments 2. Microscopy 3. Consultation 4. Lac operon + DNA and RNA isolation 5. Exercises on Mendelian genetics 6. Consultation 7. Separation techniques 1. PCR 2. Molecular cloning 3. Consultation 4. Detection of proteins 5. Clinical diagnostics 6. Consultation 7. Genomics 1st Semester 2nd Semester practice Cell Biology and Molecular Genetics

Basics of molecular biology - 1hr/week, elective course - For students with week background in biology - Exam – written Date:every Friday, 12:00-12:45 Site: Dermatology clinic Zsolt Boldogkői

Frontiers in molecular biology 2 hrs/week, elective course - The most interesting topics of biology - Exam: essay or regular exam (written or oral) Date: every Monday, 18:00-19:45 Site: Ophthalmology clinic Zsolt Boldogkői

Genetic Analysis (Molecular Medicine) - 2 hrs/2 weeks, elective course Date: Every 2nd Monday, 18:00 – 19:40 Site: decided later - On the interface of medicine and molecular biology - Invited lecturers - Exam: essay or regular exam István Belecz Zsolt Boldogkői

- 1 hr/week János Szabad Developmental genetics

Medical Molecular Biology and Genomics - 1hr/week at the 1st semester, for 4 th and 5 th -year students date: every 2nd Wednesday, 18:00-19:45 place: Educational Center (Dóm Square 13, lecture room 49. Zsolt Boldogkői

Pre-Med Course -1x2h/week lecture; 2x2 h/week seminar, in both semesters! time: xxx place: Lecture: xxxx; Seminar: xxx István Belecz Zsolt Boldogkői

Interactive Institute

Passwords for the courses Cell Biology and Molecular Genetics (lecture):Zsolt Basics of Cell Biology: Dora Cell Biology and Molecular Genetics (practice): Gyorgy Frontiers of Molecular Biology: Erno Developmental Genetics:Janos Genetic Analysis (Molecular Medicine):Istvan Medical Molecular Biology and GenomicsBelep Pre-MedPremed LECTURE PASSWORD