The early response genes c-jun and HSP-70 are induced in regional cardiac stunning in conscious mammals  Andreas Meissner, MDa, Iva Lüss, PhDb, Norbert Rolf, MDa, Peter Boknik, PhDb, Uwe Kirchhefer, MDb, Vadim Kehm, BSca, Jörg Knapp, MDb, Bettina Linck, MDb, Hartmut Lüss, PhDb, Frank U. Müller, MDb, Thomas Weber, MDa, Wilhelm Schmitz, MDb, Hugo Van Aken, MDa, Joachim Neumann, MDb  The Journal of Thoracic and Cardiovascular Surgery  Volume 119, Issue 4, Pages 820-825 (April 2000) DOI: 10.1016/S0022-5223(00)70019-5 Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

Fig. 1 Expression of mRNA for HSP-70 in stunned canine myocardium. The LAD in chronically instrumented dogs was occluded for 10 minutes followed by reperfusion until the WTF returned to 50% of the preocclusion value. Tissue was obtained from the LAD and the RCx-perfused areas. The autoradiograph of a representative Northern blot for HSP is shown. The left lane contains RNA from the RCx-perfused area, and the right lane contains RNA from the LAD-perfused area. The Journal of Thoracic and Cardiovascular Surgery 2000 119, 820-825DOI: (10.1016/S0022-5223(00)70019-5) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

Fig. 2 Expression of mRNA coding for GRP-94 in stunned canine myocardium. The LAD in chronically instrumented dogs was occluded for 10 minutes followed by reperfusion until the WTF returned to 50% of the preocclusion value. Tissue was obtained from the LAD- and the RCx-perfused areas. The autoradiograph of a representative Northern blot for GRP-94 is shown. The left lane contains RNA from the RCx-perfused area, and the right lane contains RNA from the LAD-perfused area. The Journal of Thoracic and Cardiovascular Surgery 2000 119, 820-825DOI: (10.1016/S0022-5223(00)70019-5) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

Fig. 3 Protein levels of HSP-70 in stunned canine myocardium. The LAD in chronically instrumented dogs was occluded for 10 minutes followed by reperfusion until the WTF returned to 50% of the preocclusion value. Tissue was obtained from the LAD- and the RCx-perfused areas. The autoradiograph of a representative Western blot is shown. The area of interest around 70 kDa is depicted. The left lane represents the RCx-perfused area, and the right lane shows the LAD-perfused area. The Journal of Thoracic and Cardiovascular Surgery 2000 119, 820-825DOI: (10.1016/S0022-5223(00)70019-5) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

Fig. 4 Protein levels of c-jun in stunned canine myocardium. The LAD in chronically instrumented dogs was occluded for 10 minutes followed by reperfusion until the WTF returned to 50% of the preocclusion value. Tissue was obtained from the LAD- and the RCx-perfused area. The autoradiograph of a representative Western blot is shown. The area of interest around 39 kDa is shown. The left lane represents the RCx-perfused area, and the right lane shows the LAD-perfused area. The Journal of Thoracic and Cardiovascular Surgery 2000 119, 820-825DOI: (10.1016/S0022-5223(00)70019-5) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions