GSN and DNMT1 expression are inversely correlated in a pattern associated with patient survival. GSN and DNMT1 expression are inversely correlated in a.

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Volume 118, Issue 6, Pages (June 2000)

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Molecular Therapy - Methods & Clinical Development

Histopathologic features (all images at ×10 magnification).

Volume 118, Issue 6, Pages (June 2000)

Effects of AG-221 treatment on survival and cell differentiation in an IDH2R140Q primary human AML xenograft model. Effects of AG-221 treatment on survival.

IHC staining of FFPE esophageal tissues in tissue microarrays (×20).

Representative multiplex immunofluorescence image of synovial sarcoma with increased PD-L1/PD-1/CD8 cell densities at the tumor-invasive margin demonstrating.

Treatment of human MCC tumors with intralesional IFNβ is associated with MHC-I upregulation. Treatment of human MCC tumors with intralesional IFNβ is associated.

B7-H4 expression correlates with MHC-I expression and improved prognosis in patients with breast cancer. B7-H4 expression correlates with MHC-I expression.

Kaplan–Meier survival curves of all-cause mortality in patients with idiopathic pulmonary fibrosis (IPF). Kaplan–Meier survival curves of all-cause mortality.

ROC curve for separating advanced stages (advanced BE and EA) versus early stages (BE or BE instability) using total genome-wide LOH [area under the curve.

Number of 0.5-Mb windows with chromosome lesions that reached statistical significance across patients in early (BE early and BE instability) and late.

Laser scanning analysis of the double-labeled immunofluorescence for σ (Alexa Fluor® 594; red) and p63 (Alexa Fluor® 488; green). Laser scanning.

Fig. 3 CSF1 is expressed in human melanoma.

NICD1 immunohistochemical staining in normal and tumor tissue.

Quantification of MHC-I, β2m, and T-cell subsets.

SIRT1 is downregulated in human gastric cancer (GC).

Characteristics of spontaneous HPV buccal tumors.

Autophagy restrains pancreatic inflammation and expression of pTBK1, CCL5, and PD-L1 in vivo. Autophagy restrains pancreatic inflammation and expression.

Correlation of RSPO expression to LGR5 expansion in gastric cancer.

Geographic colocalization of PD-L1+ tumor cells with infiltrating immune cells in MCC. The predominant pattern of tumor cell PD-L1 expression is at the.

IL32 is highly expressed in mycosis fungoides lesional skin.

Expression profile of RSPO1 and 2 in gastric cancer.

Association between RB pathway alterations and poor prognosis in early-stage lung adenocarcinoma patients. Association between RB pathway alterations and.

Progastrin expression in colonic tissues and Kaplan–Meier survival curves. Progastrin expression in colonic tissues and Kaplan–Meier survival curves. A,

PD-L1 expression by melanocytes is observed in geographic association with TILs but does not depend on BRAF V600E. PD-L1 expression by melanocytes is observed.

Landscape of the TME in gastric cancer and characteristics of TME subtypes. Landscape of the TME in gastric cancer and characteristics of TME subtypes.

Effects of DPM treatment on tumor volume, tumor mass, and pulmonary metastasis at experimental end point. Effects of DPM treatment on tumor volume, tumor.

LINC00092 binds with PFKFB2 to promote ovarian cancer metastasis.

Immune signatures of patients with short-, medium-, and long-term survival. Immune signatures of patients with short-, medium-, and long-term survival.

AXL is not expressed in human prostate tumors.

CD8, galectin-3, galectin-9, and the M1/M2 ratio are associated with a longer survival. CD8, galectin-3, galectin-9, and the M1/M2 ratio are associated.

Correlation between serum visfatin concentrations and the clinical stage (A) and tumor size (B, C) of HCCs. A and B, the correlations were determined by.

IL-13Rα2 expression is associated to human colon cancer progression and poor survival of patients with colorectal cancer. IL-13Rα2 expression is associated.

EMT gene expression patterns of M-Wnt and E-Wnt cells in vitro and in vivo. EMT gene expression patterns of M-Wnt and E-Wnt cells in vitro and in vivo.

ALDH1A3 expression levels are inversely correlated with the survival of patients with resectable mass-forming and advanced cholangiocarcinoma, respectively.

A, Proportion of variants detected in the MMR genes.

T-cell activation and induction of apoptosis in epithelial cells of oral lesions induced by 4-NQO. T-cell activation and induction of apoptosis in epithelial.

Mir-128 reduction in breast cancer tissues correlates chemotherapy resistance and poor patient survival. Mir-128 reduction in breast cancer tissues correlates.

Survival risk prediction analysis and application of the metastasis gene signature. Survival risk prediction analysis and application of the metastasis.

Kaplan-Meier survival analysis of p53 mutation in the overall breast tumor series. Kaplan-Meier survival analysis of p53 mutation in the overall breast.

DNA demethylation reactivates GSN expression in gastric cancer cells.

Intratumoral lymphoid aggregates are sites of postvaccination T-cell activation and regulation. Intratumoral lymphoid aggregates are sites of postvaccination.

MDC/CCL22 and MMP-2 factors are found in the melanoma microenvironment and correlate with pDC accumulation and early relapse. MDC/CCL22 and MMP-2 factors.

MYC–HOXB7–HER2 predicts clinical outcome in breast cancer patients treated with tamoxifen. MYC–HOXB7–HER2 predicts clinical outcome in breast cancer patients.

Representative images demonstrating LOH in breast cancer patients’ paired BM aspirate and primary tumors (T) at D14S62, D14S51, and D8S321, respectively.

Influence of ASGR2 expression on survival.

Kaplan–Meier curves for RFS and OS by various marker groups.

Expression of HO-1 by the FAP+/F4/80+ tumoral macrophages.

A and B, two blocks from the original specimen used for TMA demonstrated areas with varying patterns of ALK rearrangement and KRAS mutation status. A and.

Increased frequency and number of KLL-specific clonotypes in tumors is associated with improved MCC-specific survival. Increased frequency and number of.

Histology (H&E; original magnification, ×100 for B-2P/C-12P/C-64P and ×40 for C-10P; top) of small-sized lung adenocarcinomas and immunohistochemical staining.

Immunofluorescence (A-C) and IHC (D-G) analysis of XAGE-1b.

Patient stratification using survival risk prediction and BCLC staging

Progression and survival analysis.

Correlations between APOBEC expression and immune cell markers across 22 cancer types. Correlations between APOBEC expression and immune cell markers across.

In situ expression of signature genes in the Th1, Th2, Th17, and Treg pathways. In situ expression of signature genes in the Th1, Th2, Th17, and Treg pathways.

Gene expression heatmap of non–T-cell-inflamed, intermediate, and T-cell–inflamed testicular germ cell tumors from TCGA. Genes are on the row, and samples.

AXL-on tumors are heterogeneous for AXL expression and EdU incorporation. AXL-on tumors are heterogeneous for AXL expression and EdU incorporation. A,

Coculture with U937 cells enhances DNMT1 expression in gastric cancer cells. Coculture with U937 cells enhances DNMT1 expression in gastric cancer cells.

Immunohistochemical determination of TIM-3 expression in ccRCC.

CD36 expression is coordinately regulated in multiple cellular compartments. CD36 expression is coordinately regulated in multiple cellular compartments.

CD36 expression in tissue adjacent and distal to the tumor.

TAMs upregulate DNMT1 in gastric cancer cells through the CCL5/CCR5/STAT3 pathway. TAMs upregulate DNMT1 in gastric cancer cells through the CCL5/CCR5/STAT3.

Transcriptome traits and clinical characteristics of TME phenotypes in the ACRG cohort. Transcriptome traits and clinical characteristics of TME phenotypes.

Comparison of PD-L1 mAbs in IHC across multiple tumor types.

DYNLRB1, AIMP1, and NPIPA1 expression correlate with survival in neuroblastoma. DYNLRB1, AIMP1, and NPIPA1 expression correlate with survival in neuroblastoma.

The inverse correlation between PARP1 and PD-L1, PAR, and p-STAT3 expression in surgical specimens of ovarian cancer. The inverse correlation between PARP1.

Coincidence and prognostic significance of PD-1+ and CD103+ cells in HGSC. Serial sections from the 490-case TMA were stained with antibodies to CD103.

IHC staining of FFPE esophageal tissues in tissue microarrays (×20).

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GSN and DNMT1 expression are inversely correlated in a pattern associated with patient survival. GSN and DNMT1 expression are inversely correlated in a pattern associated with patient survival. A, IHC staining of DNMT1 was performed in early-stage and advanced-stage gastric cancer. Magnification: 100× (top). Images on the lower panel are high-magnification (400×) of the areas outlined by black squares. B, IF staining of GSN (green) and DNMT1 (red) was performed in early-stage and advanced-stage tumors. Original magnification: 100× (top). Images on the lower panel are high-magnification (400×) of areas outlined by white squares. C, Kaplan–Meier survival curves showed that the DNMT1HighGSNLow group had the worst patient survival than the other groups (P = 0.0406). Hao-Chen Wang et al. Cancer Immunol Res 2017;5:885-897 ©2017 by American Association for Cancer Research