How long can we preserve the pulmonary graft inside the nonheart-beating donor? Filip R Rega, MD, Arne P Neyrinck, MD, Geert M Verleden, MD, PhD, Toni.

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How long can we preserve the pulmonary graft inside the nonheart-beating donor? Filip R Rega, MD, Arne P Neyrinck, MD, Geert M Verleden, MD, PhD, Toni E Lerut, MD, PhD, Dirk E.M Van Raemdonck, MD, PhD The Annals of Thoracic Surgery Volume 77, Issue 2, Pages 438-444 (February 2004) DOI: 10.1016/S0003-4975(03)01343-2

Fig 1 Schematic overview of the experimental groups starting at death of the animals. (E = evaluation; h = hours; HBD = heart-beating donor; min = minutes; NHBD-TC3 = nonheart-beating donor plus 3 hours topical cooling; NHBD-TC6 = nonheart-beating donor plus 6 hours topical cooling.) The Annals of Thoracic Surgery 2004 77, 438-444DOI: (10.1016/S0003-4975(03)01343-2)

Fig 2 (A) Technique of topical cooling. One inflow drain and one outflow drain was inserted in each pleural cavity. (B) The two outflow drains were connected to a 5 cm H2O overflow system. The Annals of Thoracic Surgery 2004 77, 438-444DOI: (10.1016/S0003-4975(03)01343-2)

Fig 3 Endobronchial temperature decline after death in the two study groups: nonheart-beating donor plus 3 hours topical cooling (NHBD-TC3, dotted line) and nonheart-beating donor plus 6 hours topical cooling (NHBD-TC6, solid gray line). The Annals of Thoracic Surgery 2004 77, 438-444DOI: (10.1016/S0003-4975(03)01343-2)

Fig 4 Pulmonary vascular resistance in all three groups (n = 6 in each group). (HBD = heart-beating donor; Min-Max = minimum-maximum; NHBD-TC3 = nonheart-beating donor plus 3 hours topical cooling; NHBD-TC6 = nonheart-beating donor plus 6 hours topical cooling.) The Annals of Thoracic Surgery 2004 77, 438-444DOI: (10.1016/S0003-4975(03)01343-2)

Fig 5 Mean airway pressure in all three groups (n = 6 in each group). (HBD = heart-beating donor; Min-Max = minimum-maximum; NHBD-TC3 = nonheart-beating donor plus 3 hours topical cooling; NHBD-TC6 = nonheart-beating donor plus 6 hours topical cooling.) The Annals of Thoracic Surgery 2004 77, 438-444DOI: (10.1016/S0003-4975(03)01343-2)

Fig 6 Oxygenation index in all three groups (n = 6 in each group). (HBD = heart-beating donor; Min-Max = minimum-maximum; NHBD-TC3 = nonheart-beating donor plus 3 hours topical cooling; NHBD-TC6 = nonheart-beating donor plus 6 hours topical cooling.) The Annals of Thoracic Surgery 2004 77, 438-444DOI: (10.1016/S0003-4975(03)01343-2)

Fig 7 Wet-to-dry weight ratio in all three groups (n = 6 in each group). (HBD = heart-beating donor; Min-Max = minimum-maximum; NHBD-TC3 = nonheart-beating donor plus 3 hours topical cooling; NHBD-TC6 = nonheart-beating donor plus 6 hours topical cooling.) The Annals of Thoracic Surgery 2004 77, 438-444DOI: (10.1016/S0003-4975(03)01343-2)