Fecal excretion of human deoxyribonucleic acid as an index of inflammatory activity in ulcerative colitis  Francesc Casellas, Maria Antolı́n, Encarnación.

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Fecal excretion of human deoxyribonucleic acid as an index of inflammatory activity in ulcerative colitis  Francesc Casellas, Maria Antolı́n, Encarnación Varela, Ana Garcı́a-lafuente, Francisco Guarner, Natalia Borruel, José Ramón Armengol Miró, Juan-Ramón Malagelada  Clinical Gastroenterology and Hepatology  Volume 2, Issue 8, Pages 683-689 (August 2004) DOI: 10.1016/S1542-3565(04)00291-5

Figure 1 (A) Fecal DNA and (B) gut lavage DNA in controls and patients with ulcerative colitis grouped according to clinical activity (median is represented by the solid line and the 25th–75th percentile by the box). Excretion of DNA in remission patients and control individuals was similar. Patients with active disease showed significantly higher DNA levels. ∗P < 0.05 vs. active. Clinical Gastroenterology and Hepatology 2004 2, 683-689DOI: (10.1016/S1542-3565(04)00291-5)

Figure 2 (A) Fecal DNA and (B) gut lavage DNA in controls and patients with ulcerative colitis grouped according to endoscopic disease activity (median is represented by the solid line and the 25th–75th percentile by the box). Excretion of DNA in remission patients and control individuals was similar. Patients with active disease showed significantly higher DNA levels. ∗P < 0.05 vs. active. Clinical Gastroenterology and Hepatology 2004 2, 683-689DOI: (10.1016/S1542-3565(04)00291-5)

Figure 3 Correlation between (A) clinical and (B) endoscopic scores with fecal DNA excretion levels. ∗P < 0.01. Clinical Gastroenterology and Hepatology 2004 2, 683-689DOI: (10.1016/S1542-3565(04)00291-5)

Figure 4 ROC curves generated at (A) different fecal DNA levels or (B) gut lavage DNA levels relative to clinical (left panel) or endoscopic (right panel) activity. Clinical Gastroenterology and Hepatology 2004 2, 683-689DOI: (10.1016/S1542-3565(04)00291-5)