L-ICON1 is effective for the treatment of murine TNBC (4T1/Luc + GFP) in an orthotopic CDX model. L-ICON1 is effective for the treatment of murine TNBC.

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Presentation transcript:

L-ICON1 is effective for the treatment of murine TNBC (4T1/Luc + GFP) in an orthotopic CDX model. L-ICON1 is effective for the treatment of murine TNBC (4T1/Luc + GFP) in an orthotopic CDX model. Tumor growth curves (A) and mouse survival curves (B) after intratumoral injection of AdL-ICON1 or AbBlank control vectors for murine breast cancer 4T1 in an orthotopic model in Balb/c mice (n = 5 in each group). Representative results (mean ± SEM) from two independent experiments. P values were analyzed by the linear mixed model with random subject effects (A) or by Kaplan–Meier analysis (B). Zhiwei Hu et al. Cancer Immunol Res 2018;6:671-684 ©2018 by American Association for Cancer Research