Does PSA Testing Influence the Natural History of Prostate Cancer?

Slides:



Advertisements
Similar presentations
Introduction The incidence of prostate cancer in Asians is lower compared to the Westerners in men with PSA
Advertisements

What is the role of free PSA? Total PSA Range 2.5 to 4.0 ng/ml Age Range (Years) %Free PSA=60 (yrs)All Ages
Epidemiology of prostate cancer in the Umbria region of Italy: evidence of opportunistic screening effects  Francesco La Rosa, Fabrizio Stracci, Liliana.
Volume 70, Issue 3, Pages (September 2016)
Volume 68, Issue 6, Pages (December 2015)
Volume 50, Issue 1, Pages (July 2006)
Volume 52, Issue 1, Pages (July 2007)
Volume 51, Issue 2, Pages (February 2007)
The Origin of the Bone Scan as a Tumour Marker in Prostate Cancer
Testosterone Therapy in Men With Prostate Cancer
Global Trends in Testicular Cancer Incidence and Mortality
Prostate Cancer 2008: Challenges in Diagnosis and Management
Volume 71, Issue 1, Pages (January 2017)
Volume 73, Issue 6, Pages (June 2018)
Volume 71, Issue 5, Pages (May 2017)
Prostate Cancer Epidemic in Sight?
Volume 63, Issue 4, Pages (April 2013)
Bladder Cancer: A Major Public Health Issue
Volume 68, Issue 5, Pages (November 2015)
Towards Early and More Specific Diagnosis of Prostate Cancer
Diagnostic Strategies for Prostate Cancer
Ongoing Gleason Grade Migration in Localized Prostate Cancer and Implications for Use of Active Surveillance  Adam B. Weiner, Ruth Etzioni, Scott E. Eggener 
Counselling the Prostate Cancer Patient
Volume 63, Issue 4, Pages (April 2013)
Luis Martínez-Piñeiro  European Urology Supplements 
Prostate Cancer Epidemic in Sight?
Global Burden of Urologic Cancers, 1990–2013
The Origin of the Bone Scan as a Tumour Marker in Prostate Cancer
Current Status of Combined Radiation Therapy and Androgen Suppression in Locally Advanced Prostate Cancer: What Is the Way Forward?  Michel Bolla  European.
Volume 63, Issue 3, Pages (March 2013)
Volume 71, Issue 1, Pages (January 2017)
Might Men Diagnosed with Metastatic Prostate Cancer Benefit from Definitive Treatment of the Primary Tumor? A SEER-Based Study  Stephen H. Culp, Paul.
Richard C. Harkaway  European Urology Supplements 
Is It Necessary to Detect All Prostate Cancers in Men with Serum PSA Levels
Volume 50, Issue 5, Pages (November 2006)
Volume 58, Issue 3, Pages (September 2010)
Anna Grenabo Bergdahl, Erik Holmberg, Sue Moss, Jonas Hugosson
Optimising Hormone Therapy in Advanced Disease
What's New in Prostate Cancer: Highlights from Urologic and Oncologic Congresses in 2006  Michel Soulié, Nicolas Mottet, Laurent Salomon, Jacques Irani,
Jacques Irani  European Urology Supplements 
Insights into the Relationships between Prostatic Disorders and Their Potential Impact on Future Urologic Practice  Claus Roehrborn  European Urology.
The 20-Yr Outcome in Patients with Well- or Moderately Differentiated Clinically Localized Prostate Cancer Diagnosed in the Pre-PSA Era: The Prognostic.
Long-Term Hormonal Therapy: Who Would Benefit?
PSA Levels and the Probability of Prostate Cancer on Biopsy
Volume 59, Issue 4, Pages (April 2011)
The Hallmarks of BPH Progression and Risk Factors
How and When to Take Prostate Biopsies
Challenges and Opportunities in Hormone-Resistant Prostate Cancer
Thomas Steuber, Matthew Frank O'Brien, Hans Lilja  European Urology 
Epidemiology of Renal Cell Carcinoma
Improving Outcomes in Prostate Cancer: Time to Tackle Bone Disorders
A Multidisciplinary Team Approach for the Optimal Clinical Management of Metastatic Hormone-Refractory Prostate Cancer—Case Study  John Fitzpatrick  European.
European Urology Oncology
Prostate Cancer 2008: Challenges in Diagnosis and Management
Richard Berges  European Urology Supplements 
Axel Heidenreich  European Urology Supplements 
Prognostic Factors in Non–Muscle-Invasive Bladder Tumors
Edith Canby-Hagino, Javier Hernandez, Timothy C. Brand, Ian Thompson 
Manfred Wirth, Peter Iversen, David McLeod, William See 
Volume 51, Issue 2, Pages (February 2007)
Volume 54, Issue 3, Pages (September 2008)
Oncoforum Urology: Prostate Cancer 2008 at a Glance
Projected National Impact of Colorectal Cancer Screening on Clinical and Economic Outcomes and Health Services Demand  Uri Ladabaum, Kenneth Song  Gastroenterology 
Epidemiology and Demographics of Prostatitis
New Research Findings on Clinical Benefits of Bisphosphonates in Patients With Advanced Prostate Cancer  Noel W. Clarke  European Urology Supplements 
Axel Heidenreich  European Urology Supplements 
Quality of life: An outcomes perspective
Michael Marberger  European Urology Supplements 
Introduction European Urology Supplements
Assessing a Patient’s Individual Risk of Biopsy-detectable Prostate Cancer: Be Aware of Case Mix Heterogeneity and A Priori Likelihood  Jan F.M. Verbeek,
Presentation transcript:

Does PSA Testing Influence the Natural History of Prostate Cancer? John Anderson  European Urology Supplements  Volume 1, Issue 5, Pages 3-10 (August 2002) DOI: 10.1016/S1569-9056(02)00047-7

Fig. 1 Disease-specific mortality by tumour grade in a cohort of 451 men aged 65–75 years at diagnosis and managed conservatively [10] (reproduced with permission). European Urology Supplements 2002 1, 3-10DOI: (10.1016/S1569-9056(02)00047-7)

Fig. 2 Trial profile of the Quebec Prostate Cancer Screening Program (man-years [m-y]) [21] (reproduced with permission). European Urology Supplements 2002 1, 3-10DOI: (10.1016/S1569-9056(02)00047-7)

Fig. 3 Proportion of men in the ERSPC and PLCO studies with a screening indication for biopsy [23] (reproduced with permission). European Urology Supplements 2002 1, 3-10DOI: (10.1016/S1569-9056(02)00047-7)

Fig. 4 Age-adjusted rates of prostate cancer: (a) incidence, and (b) mortality in the SEER Program, 1973–1996. The shaded areas on the figures represent the period following the introduction of PSA testing [24] (reproduced with permission). European Urology Supplements 2002 1, 3-10DOI: (10.1016/S1569-9056(02)00047-7)