Volume 67, Issue 6, Pages (June 2005)

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Volume 67, Issue 6, Pages 2313-2320 (June 2005) Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy Marion Haubitz, Stefan Wittke, Eva M. Weissinger, Michael Walden, Harald D. Rupprecht, Jergen Floege, Hermann Haller, Harald Mischak Kidney International Volume 67, Issue 6, Pages 2313-2320 (June 2005) DOI: 10.1111/j.1523-1755.2005.00335.x Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 1 Protein contour plots of healthy volunteers (A), patients with IgA nephropathy (IgAN) (B) and patients with membranous nephropathy (MN) (C). The molecular mass per charge is shown on the left and plotted against the migration time in the capillary electrophoresis (CE) (50 minutes). The color-coded scale, indicating the intensity of the signal, is correlated to the concentration of proteins and peptides in the sample. Kidney International 2005 67, 2313-2320DOI: (10.1111/j.1523-1755.2005.00335.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 2 Identification of potential biomarker polypeptides with mass spectrometry-mass spectrometry (MS-MS). The polypeptide with the mass of 2057.3 was further examined using matrix-assisted laser desorption/ionization time-of-flight (MALDI TOF-TOF). The MS-MS spectrum with the annotations of the individual peaks and the sequences of the peptide is shown. Kidney International 2005 67, 2313-2320DOI: (10.1111/j.1523-1755.2005.00335.x) Copyright © 2005 International Society of Nephrology Terms and Conditions