Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial A. Pesonen, R. Suojaranta-Ylinen,

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Presentation transcript:

Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial A. Pesonen, R. Suojaranta-Ylinen, E. Hammarén, V.K. Kontinen, P. Raivio, P. Tarkkila, P.H. Rosenberg British Journal of Anaesthesia Volume 106, Issue 6, Pages 873-881 (June 2011) DOI: 10.1093/bja/aer083 Copyright © 2011 The Author(s) Terms and Conditions

Fig 1 Patient flow chart. British Journal of Anaesthesia 2011 106, 873-881DOI: (10.1093/bja/aer083) Copyright © 2011 The Author(s) Terms and Conditions

Fig 2 Cumulative oral oxycodone consumption in the pregabalin and the placebo groups during 5 postoperative days (POD) after cardiac surgery. The box plots show the median, inter-quartile range, and standard deviation. *P<0.05. British Journal of Anaesthesia 2011 106, 873-881DOI: (10.1093/bja/aer083) Copyright © 2011 The Author(s) Terms and Conditions

Fig 3 Percentage of the patients whose pain intensity measured on the VRS (0–4) was ≥2 in the ICU after extubation. *P<0.05. British Journal of Anaesthesia 2011 106, 873-881DOI: (10.1093/bja/aer083) Copyright © 2011 The Author(s) Terms and Conditions