University of Nevada, Las Vegas (UNLV) Howard R University of Nevada, Las Vegas (UNLV) Howard R. Hughes College of Engineering Overview of Biomedical Engineering Research 1/25/2011 http://engineering.unlv.edu/ 1 1

Howard R. Hughes College of Engineering at UNLV Biomedical Engineering Research at the HRH College of Engineering, UNLV Howard R. Hughes College of Engineering at UNLV Dr. Rama Venkat Dean, College of Engineering Phone: (702) 895-1094 Email: rama.venkat@unlv.edu Dr. Mohamed Trabia Associate Dean, College of Engineering Phone: (702) 895-0957 Email: mohamed.trabia@unlv.edu Biomedical engineering is a research area in which the College of Engineering at UNLV would like to see a sustained growth. Our faculty has been involved in many related activities over the last decade. The combination of experimental and computational facilities within the college is a basis for future collaboration with other entities in Southern Nevada. We would like to introduce you to some of our researchers. Please feel to contact us if we can help with your projects and initiatives. http://engineering.unlv.edu/ 2 2

Biomedical Engineering Research at the HRH College of Engineering, UNLV Why UNLV? Las Vegas is a dynamic city with a population that includes multiple ethnicities and age groups. Las Vegas has attracted several organizations that are active in medical research including: UNLV University of Nevada School of Medicine Nevada Cancer Institute Cleveland Clinic Lou Ruvo Center for Brain Health In the meantime, multiple entities within UNLV have been active in advancing biomedical research: UNLV School of Allied Health Sciences UNLV School of Community Health Sciences UNLV School of Dental Medicine UNLV College of Sciences UNLV College of Engineering We strongly feel that this is the right time to establish synergy between these entities to advance scientific knowledge and economy of Southern Nevada. 3 3

Biomedical Engineering Research at the HRH College of Engineering, UNLV Faculty involved in Energy Research Dr. Robert F. Boehm Distinguished Professor, Department of Mechanical Engineering Dr. Yitung Chen Professor, Department of Mechanical Engineering Dr. Shahram Latifi, P.E. Professor, Department of Electrical and Computer Engineering Dr. Edward Neumann, P.E., C.P. Professor, Department of Civil and Environmental Engineering Dr. Brendan O’Toole Associate Professor, Department of Mechanical Engineering Director, Center for Materials and Structures Dr. Darrell Pepper Director, Nevada Center for Advanced Computational Methods Dr. Emma Regentova Associate Professor, Department of Electrical and Computer Engineering Dr. Mohamed Trabia Professor, Department of Mechanical Engineering Associate Dean for Research, Graduate Studies, and Computing Dr. Woosoon Yim Professor and Chair, Department of Mechanical Engineering Director of Intelligent Structures and Control Laboratory Dr. Evangelos Yfantis Professor, Computer Science Dr. Hui Zhao Assistant Professor, Department of Mechanical Engineering 4 4

Email: bob.boehm@unlv.edu Phone: (702) 895-4160 Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Robert F. Boehm Distinguished Professor, Department of Mechanical Engineering Bio-fluid and heat transfer Thermal modulation Analysis of esophageal acid reflux phenomena Ultrasound heating for biological applications Email: bob.boehm@unlv.edu Phone: (702) 895-4160 5 5

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Yitung Chen Professor, Department of Mechanical Engineering Pulmonary air flow and cardiovascular blood flow modeling Biosensor design Pharmacokinetics Biomolecular simulation Computational fluid dynamics Computational heat transfer and mass transfer Email: uuchen@nscee.edu Phone: (702) 895-1202 6 6

Email: shahram.latifi@unlv.edu Phone: (702) 895-4106 Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Shahram Latifi, P.E. Professor, Department of Electrical and Computer Engineering Medical imaging Computer-aided diagnostic systems Data compression Email: shahram.latifi@unlv.edu Phone: (702) 895-4106 7 7

Email: Edward.Neumann@unlv.edu Phone: (702) 895-1702 Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Edward Neumann, P.E., C.P. Professor and Chair, Department of Civil and Environmental Engineering Director, Center for Disability and Applied Biomechanics Orthopedic biomechanics Prosthetics systems engineering Human factors and ergonomics Email: Edward.Neumann@unlv.edu Phone: (702) 895-1702 8 8

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Brendan O’Toole Associate Professor, Department of Mechanical Engineering Director, Center for Materials and Structures Strength and stiffness of bones Analysis of composite prosthetics Evaluation of new orthodontic materials and methods Analysis and prevention of injuries due to shock or impact loads Email: bj@me.unlv.edu Phone: (702) 895-3885 9 9

Email: Darrell.pepper@unlv.edu Phone: (702) 895-1056 Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Darrell Pepper, Professor Department of Mechanical Engineering Director, Nevada Center for Advanced Computational Methods Computational fluid dynamics, heat transfer, and species transport Advanced computational techniques Indoor air quality Contaminant transport Email: Darrell.pepper@unlv.edu Phone: (702) 895-1056 10 10 10

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Emma Regentova Associate Professor, Department of Electrical and Computer Engineering Breast cancer research Detection of microcalcification clusters in digital mammograms Email: regent@ee.unlv.edu Phone: (702) 895-3187 11 11

Email: Mohamed.Trabia@unlv.edu Phone: (702) 895-0957 Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Mohamed Trabia Professor, Department of Mechanical Engineering Associate Dean for Research, Graduate Studies, and Computing Optimization of human-powered vehicle design Bone fixation systems design and analysis Fingertip force measurement and characterization Design of an electronic Braille reading system Email: Mohamed.Trabia@unlv.edu Phone: (702) 895-0957 12 12

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Evangelos Yfantis Professor, School of Computer Science Medical images and video Statistical pattern recognition and classification algorithms of medical images and video Lossless compression of medical images and video Archiving noise-free, secure, and fast DICOM medical images, video, and data transmission Telemedicine Computer simulation of human anatomy Minimally invasive methods using computer vision Email: yfantis@cs.unlv.edu Phone: (702) 895-3536 13 13

Email: woosoon.yim@unlv.edu Phone: (702) 895-0956 Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Woosoon Yim Professor and Chair, Department of Mechanical Engineering Director of Intelligent Structures and Control Laboratory Bio-sensor and actuator development Biomechanical study of upper airway morphology and its correlation with severity of obstructive sleep apnea Biologically inspired design of robotic devices Email: woosoon.yim@unlv.edu Phone: (702) 895-0956 14 14

Email: hui.zhao@unlv.edu Phone: (702) 895- Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Hui Zhao Assistant Professor, Department of Mechanical Engineering Micro- and nano-fluidics Electrokinetic transport Nanoparticle and bio-molecule assembly Manipulation, and separation Lab-on-a-chip technologies toward biomedical diagnostics and analysis Email: hui.zhao@unlv.edu Phone: (702) 895- 15 15

Biomedical Engineering Research CV and Publications 16 16

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Robert F. Boehm Distinguished Professor, Department of Mechanical Engineering Contact Information UNLV 4505 S. Maryland Parkway Box 454027 Las Vegas, NV 89154-4027 Phone: (702) 895-4160 Email: bob.boehm@unlv.edu Fax: (702) 895-3936 Website: http://www.me.unlv.edu/GeneralInfo/faculty/boehm.htm Specialties Bio-fluid and heat transfer Thermal modulation Analysis of esophageal acid reflux phenomena Ultrasound heating for biological applications 17 17

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Robert F. Boehm Distinguished Professor, Department of Mechanical Engineering Brief Description of Recent Projects Thermistor Probe Heating of a Transplanted Kidney to Assess Perfusion Rates External to Organ Analysis of a Percutaneous Transluminal Microwave Angioplasty System Applications of Lasers on Human Teeth for Anticaries Protective Procedures Publications relating to Biomedical Engineering “2-D Axisymmetric Finite Difference Modeling of Thermistor Probe Heating on the Kidney,” Proceedings of the 2003 ASME Summer Heat Transfer Conference, 2003 (with F. Brown and G. Shen) “Numerical Simulation of a Gastroesophageal Reflux Episode,” Advances in Bioengineering, 1998 (Editor A. P. Yoganathan), BED-Vol. 39, ASME, New York, pp. 359-360 (with Y. T. Chen and A. Little). "A Finite Difference Heat Transfer Analysis of a Percutaneous Transluminal Microwave Angioplasty System," Journal of Biomechanical Engineering, 1993, pp. 441-446 (with L. Young). “Regeneration of Immunologically-Active Surfaces by Thermal Modulation Methods," 1989 ASME Winter Annual Meeting (with Y.-T. Chen, D. Christensen and J. Andrade). "Measurement of the Reflectance of Tooth Enamel," Journal of Heat Transfer, August 1987, pp. 812-815 (with G. Cunnington.) "Heat Transfer in Teeth," Chapter 24, Heat Transfer in Medicine and Biology, Vol. 2, (A. Shitzer and R. C. Eberhard, Editors) Plenum Press, 1985 . "Thermal Stress Effects and Surface Cracking Associated with Laser Use on Human Teeth," Journal of Biomechanical Engineering, Vol. 99, pp. 188-194, 1977 (with J. Rich, J. Webster and S. Janke). "Laser Processes in Preventive Dentistry," Optical Engineering, Vol. 16, No. 5, pp. 493-496, 1977 (with T. Baechler, J. Webster and S. Janke). "Temperatures in Human Teeth Due to Laser Heating," ASME Paper 75-WA/Bio-8, 1975 (with M. J. Chen and C. K. Blair). 18 18

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Yitung Chen Professor, Department of Mechanical Engineering Contact Information UNLV 4505 S. Maryland Parkway Box 454027 Las Vegas, NV 89154-4027 Phone: (702) 895-1202 Email: uuchen@nscee.edu Fax: (702) 895-4922 Website: http://www.cer.unlv.edu/cer/Personnel/YitungChen/tabid/131/Default.aspx Specialties Pulmonary air flow and cardiovascular blood flow modeling Biosensor design Pharmacokinetics Biomolecule simulation Computational fluid dynamics Computational heat transfer and mass transfer 19 19

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Yitung Chen Professor, Department of Mechanical Engineering Brief description of recent projects Computational fluid dynamics (CFD) studies of airflow in a digital reference model of the 17-generation airway (bronchial tree) were accomplished using numerical modeling, based on the anatomical model. The lung model consists of 6.744e6 unstructured tetrahedral computational cells. A steady-state airflow rate was used to simulate the transient turbulent flow regime using a large eddy simulation turbulence model. It is demonstrated that the nature of the secondary vortical flows, which develop in such asymmetric airways, varies with the specific anatomical characteristics of the branching conduits. Publications relevant to Biomedical Engineering Tevfik Gemci, Valery Ponyavin, Yitung Chen, Huajun Chen, Richard Collins, “Computational Model of Airflow in Upper 17 Generations of Human Respiratory Tract,” Journal of Biomechanics, 41, (2008) pp.2047-2054. Tevfik Gemci, Valery Ponyavin, Yitung Chen, Huajun Chen, Richard Collins, “CFD Simulation of Airflow in a 17-generation Digital Reference Model of the Human Bronchial Tree,” Series on Biomechanics, Vol.23, No.1, pp.5-18, 2007 20 20

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Shahram Latifi, P.E. Professor, Department of Electrical and Computer Engineering Contact Information UNLV 4505 S. Maryland Parkway Box 454027 Las Vegas, NV 89154-4027 Phone: (702) 895-4016 Email: shahram.latifi@unlv.edu Fax: (702) 895-4075 Website: http://www.egr.unlv.edu/~latifi/ Specialties Medical imaging Computer-aided diagnostic systems Data compression 21 21

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Shahram Latifi, P.E. Professor, Department of Electrical and Computer Engineering Brief description of recent projects “Near lossless Compression of Medical Images”, CRAY Research Inc., March 1995. “Development and Evaluation of Medical Image Compression Techniques”, CRAY Research Inc., January 1994. “An Image acquisition System for Medical Applications”, UNLV, December 1998 (Student Thesis: Melerick H Mitchell).          Relevant publications to Biomedical Engineering N. Balaraman and S. Latifi, “A Survey of Lossless Compression Algorithms for Medical Applications”, Internatioanl Symposium on Intelligent Automation and Control, ISSCI-061, pp. 1-6, Anchorage, Alaska, May 1998. 22 22

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Edward Neumann, P.E., C.P. Professor and Chair, Department of Civil and Environmental Engineering Director, Center for Disability and Applied Biomechanics Contact Information UNLV 4505 S. Maryland Parkway Box 454027 Las Vegas, NV 89154-4015 Phone: (702) 895-1072 Email: Edward.Neumann@unlv.edu Fax: (702) 895-3936 Website: Specialties Orthopedic biomechanics Prosthetics systems engineering Human factors and ergonomics 23 23

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Edward Neumann, P.E., C.P. Professor and Chair, Department of Civil and Environmental Engineering Brief description of recent projects Three-Credit-Hour Semester Courses Developed and Taught at UNLV in Biomechanics, Prosthetics, and Related Areas: Analysis of Human Motion, Prosthetic Systems Engineering, Orthopedic Biomechanics, Ergonomics, Human Factors in Transportation Engineering. Expertise and experience in the use of F-scan and F-socket pressure sensing systems and Vicon motion capture systems. Prosthetics research expertise involving socket pressure and comfort, and quantitative gait analysis. Orthotics research experience in energy storage and return for AFOs constructed from composite materials. Clinical experience in all aspects of patient management including measurement, modification, fabrication, fitting, and repair of transradial cable operated prostheses; transtibial and transfemoral prostheses.   Relevant publications to Biomedical Engineering Neumann ES. Measurement of Socket Discomfort - Part I: Pressure Sensation. Journal of Prosthetics and Orthotics. 13:4, Dec 2001, pp. 99 - 110;  Neumann ES. Measurement of Socket Discomfort - Part II: Signal Detection. Journal of Prosthetics and Orthotics. 13:4, Dec 2001, pp 111 - 122;  Neumann ES, Wong JS, Drollinger RL. Concepts of Pressure in an Ischial Containment Socket: Measurement. Journal of Prosthetics and Orthotics. 17:1, Jan 2005, pp. 2-11.  Neumann ES, Wong JS, Drollinger RL. Concepts of Pressure in an Ischial Containment Socket: Perception. Journal of Prosthetics and Orthotics. 17:1, Jan 2005, pp. 12-20.  Neumann ES. State-of-the-Science Review of Transtibial Prosthesis Alignment Perturbations. Journal of Prosthetics and Orthotics. 2009:21 (4) p174-193. LICENSES AND CERTIFICATIONS Licensed Professional Engineer (P.E.): West Virginia (inactive), Nevada (active) Certified Prosthetist (CP) ABC #2944 24 24

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Brendan O’Toole Associate Professor, Department of Mechanical Engineering Director, Center for Materials and Structures Contact Information UNLV 4505 S. Maryland Parkway Box 454027 Las Vegas, NV 89154-4027 Phone: (702) 895-3885 Email: bj@me.unlv.edu Fax: (702) 895- 3996 Website: http://www.egr.unlv.edu/~bj/ Specialties Strength and stiffness of bones Analysis of composite prosthetics Evaluation of new orthodontic materials and methods Analysis and prevention of injuries due to shock or impact loads 25 25

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Brendan O’Toole Associate Professor, Department of Mechanical Engineering Director, Center for Materials and Structures Orthodontic Related Projects Shock Absorbing Properties of Elastomeric Mouth Pieces Friction of Alternative Orthodontic Ligatures Experimental Evaluation of the Failure of Solder Joints in Dental Wire Connections Shear Testing of Orthodontic Brackets Retention of Thermoformed Aligners with Varying Mounting Brackets   Prosthetic Related Projects Design and Fabrication of Polymer Composite Ankle Foot Orthosis (AFO) Experimental Evaluation of the Performance of AFO’s in situ and in a Laboratory Environment Other Projects Experimental Characterization of Bone Strength and Flexural Stiffness in Ground Squirrels Computational Analysis and Geometric Optimization of Titanium Mesh Implant Structures for Facial Reconstruction Relevant publications to Biomedical Engineering B. O’Toole, M. Hawkins, E. Neumann, M. Warner, “Strain Analysis of a composite ankle-foot orthosis”, accepted to the World Journal of Engineering, July 2009. Jenifer C. Utz, Stacy Nelson, Brendan J. O’Toole, and Frank van Breukelen, “Bone strength is maintained after 8 months of inactivity in hibernating golden-mantled ground squirrels, Spermophilus lateralis”, Accepted to Journal of Experimental Biology, May 2009. Mathew L. Jones, James Mah, and Brendan O’Toole, “Retention of Thermoformed Aligners with Various Shapes and Orientations of Attachments”, Journal of Clinic Orthodontics, v XLIII n 2, pp 113-117, February 2009. 26 26

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Darrell Pepper Professor, Department of Mechanical Engineering Director, Nevada Center for Advanced Computational Methods Contact Information 4505 S. Maryland Parkway, SEB 2174 Las Vegas, NV 89154-4027 Phone: (702) 895-1056 Fax: (702) 895-0498 Email: Darrell.pepper@unlv.edu Website: http://ncacm.unlv.edu/HTML/staff/faculty/pepper/faculty_pepper.html Specialties Computational Fluid Dynamics, heat transfer and species transport Advanced computational techniques 27 27 27

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Darrell Pepper Recent Publications Pepper, D. W., A. Kassab, and E. Divo (to appear 2011): Finite Element, Boundary Element, and Meshless Methods, ASME Press, NY, NY. Pepper, D. W. (to appear 2011): Environmental Fluid Mechanics, McGraw-Hill Yearbook Pepper, D. W. (2010): Meshless Methods, Scholarpedia  Pepper, D. W. and D. B. Carrington (2009): Modeling Indoor Air Pollution, Imperial College Press, London, UK, 346 p.  Pepper, D. W. and J. C. Heinrich (2006): The Finite Element Method: Basic Concepts and Applications, Taylor and Francis, New York, NY, 2nd Ed., 312 p. Pepper, D. W. (2006), “Chapter 7: Meshless Methods,” Handbook of Numerical Heat Transfer, 2nd Ed., W. J. Minkowycz et al (Eds.), John Wiley and Sons. Pepper, D. W. and J. M. Lombardo (2006), “Chapter 27: High Performance Computing for Heat Transfer,” Handbook of Numerical Heat Transfer, 2nd Ed., W. J. Minkowycz et al (Eds.), John Wiley and Sons. Pepper, D. W. and X. Wang (2009), “An h-adaptive Finite Element Technique for Constructing 3-D Wind Fields,” J. Appl. Meteor. & Climatology. Wang, X. and D. W. Pepper (2009), “An Adaptive Numerical Model for Contaminant Dispersion in Air,” Int. J. Num. Meth. in Fluids. Wang, X. and D. W. Pepper, D. W. (2009), "An hp-Adaptive Procedure for Modeling Indoor Contaminant Dispersion,” Comput. Modeling in. Engr. and Sci., Tech Science Press.  Pepper, D. W. and X. Wang (2009), "An hp-adaptive Finite Element Model for Heat Transfer within Partitioned Enclosures,” Int. J. Num. Meth. Fluid Flow and Heat Transfer. 28 28 28

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Emma Regentova Associate Professor, Department of Electrical and Computer Engineering Contact Information UNLV 4505 S. Maryland Parkway Box 454027 Las Vegas, NV 89154-4027 Phone: (702) 895-3187 Email: regent@ee.unlv.edu Fax: (702) 895-4075 Website: http://www.ee.unlv.edu/~regent/ Specialties Breast cancer research Detection of microcalcification in digital mammograms 29 29

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Emma Regentova Professor, Department of Electrical and Computer Engineering  Relevant publications to Biomedical Engineering E. Regentova,L. Zhang , J Zheng, G. Veni, Microcalcification detection based on wavelet domain hidden Markov tree model: Study for inclusion to computer aided diagnostic prompting system, Medical Physics, June 2007, Volume 34, Issue 6, pp. 2206-2219 J. Zheng, E. Regentova, Independent Component Analysis for Microcalcifications Detection in Digital Mammograms, AJICT, Vol. 4, No. 2, June 2008, pp.59-64. G. Veni, E. E. Regentova, A.K. Mandava, A New Method of Detecting Microcalcification Clusters for Computer Aided Digital Mammography, Nineteenth International Conference On Systems Engineering (ICSENG 2008), Las Vegas, August 19-21,2008, pp. 532 – 537 G. Veni, E.E.Regentova, L.Zhang, Detection of Clustered Microcalcifications using SUSAN Edge Detector, Adaptive Contrast Thresholding and Spatial filters, International Conference on Image Analysis and Recognition June 23-28, Porto, Portugal, 2008, pp.837-843. 30 30

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Mohamed Trabia Professor, Department of Mechanical Engineering Associate Dean for Research, Graduate Studies, and Computing Contact Information UNLV 4505 S. Maryland Parkway Box 454027 Las Vegas, NV 89154-4027 Phone: (702) 895-0957 Email: Mohamed.Trabia@unlv.edu Fax: (702) 895-4059 Website: www.me.unlv.edu/~mbt Specialties Optimization of human-powered vehicle design Bone fixation systems design and analysis Fingertip force measurement and characterization Design of an electronic Braille reading system 31 31

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Mohamed Trabia Professor, Department of Mechanical Engineering Associate Dean for Research, Graduate Studies, and Computing Relevant publications to Biomedical Engineering M. Saadeh and M. Trabia, “Development of a Measuring System of Contact Force for Braille Reading Using a Six-Axis Force Sensor” 2010 ASME International Mechanical Engineering Congress and Exposition, Vancouver, Canada, November 2010. M. Saadeh, M. Trabia, Y. Shen, and M. Fadali, “Design of a Wearable Fingertip Haptic Braille Device,” 2010 Design of Medical Devices Conference, Minneapolis, MN, April, 2010. M. Trabia, K. Zabotkin, and R. Wang, “Design of a V-Plate-Wire Mandibular Fixation System,” 2001 ASME International Mechanical Engineering Congress and Exposition, New York, New York, November 2001. Y. Lei, M. Trabia, and D. Too, “Optimization of the Seating Position in a Human-Powered Vehicle,” Biomechanics in Sport XI, pp. 115-119, presented at the 11th Annual Meeting of the International Society of Biomechanics in Sport, Amherst, Massachusetts, June 1993.   Approved Patent 20070156147, Bone fixation device and method Patent under Consideration: 20060235407, Apparatus and methods for bone fracture reduction and fixation 32 32

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Evangelos Yfantis Professor , School of Computer Science Contact Information UNLV 4505 S. Maryland Parkway Box 454027 Las Vegas, NV 89154-4027 Phone: (702) 895-3536 Email: yfantis@cs.unlv.edu Website: www.ICIS.cs.unlv.edu Specialties Bio-sensor development Actuator development 33 33

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Evangelos Yfantis Professor , School of Computer Science Brief Description of Recent Projects Computerized Medical Forms Detection, Medical Records Project DOE HCI Computer Vision Project for NASA Telemedicine   Recent Publications relating to Biomedical Engineering E. A. Yfantis, et al. , “An Algorithm for Cancer Recognition of Ultrasound Images,” International Journal on Artificial Intelligence Tools, Vol.9, No.2, pp. 265-276. T. Loch, E. A. Yfantis, et al, “Artificial Neural Network of Prostatic Transrectal Ultrasound,” The Prostate Journal, Vol. 39, pp. 198-204. E. A. Yfantis, et al, “Efficient Image Compression Algorithm for Computer Animated Images,” Journal of Electronic Imaging, Vol. 1, No. 4, pp. 381-387. E. A. Yfantis, et al. “Robot Vision and Video Transmission,” Transactions on Communications,” ISSN 1109-2742, Vol. 9, No. 8, pp. 515-523. J. Adams, E. A. Yfantis, D. Curtis, and T. Pack, “Feature Extraction Mrthods for Form Recognition Applications,” Transactions on Information Science and Applications, Vol. 3, No. 3, pp. 666-671. G. Bebis, E. A. Yfantis, et al, “Generic Object Recognition Using Combinations of Views,” IEEE Transactions on Evolutionary Computation, Vol. 6, No. 2, pp. 132-146. E. A. Yfantis, et al, “A Computer Algorithm for Cancer Recognition on Ultrasound Images of Prostate Tissue,” Proceedings of the IEEE International Conference on Information Intelligence and systems, Oct. 31-Nov. 3, Bethesda, Maryland, pp. 34-39, 1999. E. A. Yfantis, et al, “An OCR-Independent Character Segmentation Using shortest Path in Grayscale Document Images, IEEE proceedings of the Sixth International Confeence on Machine Learning and Applications, Cincinnati Ohio, Dec. 13-15, 2007, pp. 142-147. E. A. Yfantis, et al, “A Hierarchical feature Docomposition Clustering Algorithm for Unsupervised Classification and Document Image Types,” IEEE proceedings of the Sixth International Confeence on Machine Learning and Applications, Cincinnati Ohio, Dec. 13-15, 2007, pp 423-428 A. Angelopoulos, E. A. Yfantis, et al, “On Motion and Noise Detection In Digital Video,” Proc. Of the ACM Symposium on Applied Computing, Las Vegas, NV. March 11-14, 2001, pp. 312-315. E. A. Yfantis, “ An Algorithm for Key-Frame Detection in Digital Video,” Proc. Of the ACM Symposium on Applied Computing, Las Vegas, NV. March 11-14, 2001, pp. 309-311 34 34

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Woosoon Yim Professor and Chair, Department of Mechanical Engineering Director of Intelligent Structures and Control Laboratory Contact Information UNLV 4505 S. Maryland Parkway Box 454027 Las Vegas, NV 89154-4027 Phone: (702) 895-0956 Email: woosoon.yim@unlv.edu Fax: (702) 895-3936 Website: http://www.me.unlv.edu/~wy/ Specialties Bio-sensor development Actuator development 35 35

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Woosoon Yim Professor and Chair, Department of Mechanical Engineering Director of Intelligent Structures and Control Laboratory Recent Projects Biomechanial study of upper airway morphology and its correlation with severity of obstructive sleep apnea 36 36

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Hui Zhao Assistant Professor, Department of Mechanical Engineering Contact Information 505 S. Maryland Parkway Box 454027 Las Vegas, NV 89154-4027 Phone: (702) 895-1463 Email: hui.zhao@unlv.edu Fax: (702) 895-3936 Website: http://nanotechnology.unlv.edu/zhao.htm Specialties Micro- and nano-fluidics Electrokinetic transport Nanoparticle and bio-molecule assembly Manipulation, and separation Lab-on-a-chip technologies toward biomedical diagnostics and analysis 37 37

Biomedical Engineering Research at the HRH College of Engineering, UNLV Dr. Hui Zhao Assistant Professor, Department of Mechanical Engineering Recent Projects Study the fundamentals of micro/nano fluidics Design and model novel mixers and pumps using electrokinetic phenomena integrated into a lab-on-a-chip device towards automatic and fast detection and diagnostics Study nanoparticle or biomolecule’s properties and propose novel techniques using electric fields to sort, separate, and immobilize cells and biomolecules. Relevant publications to Biomedical Engineering Zhao, H., 2010, Streaming potential generated by a pressure-driven flow over a super-hydrophobic surface, submitted to Journal of Fluid Mechanics. Zhao, H., 2010, Electro-osmotic flow over a charged superhydrophobic surface, Physical Review E, 81, 066314. Zhao, H., 2010, On the Influence of Ion Excluded Volume (Steric) Effects on the Double Layer Polarization of a Non- Conducting Nano Particle in an AC Field, Journal of Physical Chemistry C, 18, 8389-8397. Zhao, H., 2010, on the Effect of Hydrodynamic Slip on the Polarization of a Non-conducting Spherical Particle in an AC Field, Physics of Fluids,7, 072004. Zhao, H. and Bau, H. H., 2010, the Polarization of Nanorods Submerged in an Electrolyte Solution and Subjected to an AC Electric field, Langmuir, 26, 5412-5420. Zhao, H. and Bau, H. H., 2009, the Polarization of a Non-conducting Nano Spherical Particle in the presence of a thick Electric double layer, Journal of Colloid and Interface Science, 333, 663-671. Zhao, H. and Bau, H. H., 2008, the Effect of Double Layer Polarization on the Forces that Act on a Nanosize Cylindrical Particle in an AC Electric Field, Langmuir, 24, 6050-6059. Zhao, H. and Bau, H. H., 2007, the Effect of Secondary Flows on Taylor-Aris Dispersion, Analytical Chemistry, 79, 7792-7798. Zhao, H. and Bau, H. H., 2007, a Microfluidic Chaotic Stirrer Utilizing Induced-Charge Electro-osmosis, Physical Review E, 75, 066217. (selected for the July 9, 2007 issue of Virtual Journal of Nanoscale Science & Technology). Zhao, H. and Bau, H. H., 2007, on the Effect of Induced Electro-Osmosis on a Cylindrical Particle Next to a Surface, Langmuir, 23, 4053-4063. Arsenault, M. E., Zhao, H., Purohit, P. K., Goldman, Y. E., and Bau, H. H., 2007, Confinement and Manipulation of Actin Filaments by Electric Fields, Biophysical Journal Letter. 93, L42-L44. 38 38

Biomedical Engineering Research at the HRH College of Engineering, UNLV Additional Resources UNLV School of Allied Health Sciences (http://alliedhealth.unlv.edu/) UNLV School of Community Health Sciences (http://publichealth.unlv.edu/) UNLV School of Dental Medicine (http://dentalschool.unlv.edu/) UNLV College of Sciences (http://sciences.unlv.edu/) UNLV College of Engineering (http://engineering.unlv.edu/) University of Nevada School of Medicine (http://www.medicine.nevada.edu/) Nevada Cancer Institute (http://www.nevadacancerinstitute.org/) Cleveland Clinic Lou Ruvo Center for Brain Health (http://www.keepmemoryalive.org/Pages/default.aspx) 39 39