Cell Communication (Signaling) Part 3 AP Biology Cell Communication (Signaling) Part 3
Kinases “turn on” processes Phosphotases “turn off” processes
Small signal produces a BIG response
The Big picture Growth factor Reception Receptor Phosphorylation cascade Transduction CYTOPLASM Inactive transcription factor Active transcription factor Response P DNA Gene NUCLEUS mRNA
Scaffolding Proteins Signal Plasma molecule membrane Receptor Three different protein kinases Scaffolding protein
Tyrosine – Kinase Receptor (Evolution – Change over TIME)