Cell Communication (Signaling) Part 3

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Cell Communication (Signaling) Part 3 AP Biology Cell Communication (Signaling) Part 3

Kinases “turn on” processes Phosphotases “turn off” processes

Small signal produces a BIG response

The Big picture Growth factor Reception Receptor Phosphorylation cascade Transduction CYTOPLASM Inactive transcription factor Active transcription factor Response P DNA Gene NUCLEUS mRNA

Scaffolding Proteins Signal Plasma molecule membrane Receptor Three different protein kinases Scaffolding protein

Tyrosine – Kinase Receptor (Evolution – Change over TIME)