Fig. 7 Analysis of the bacterial nidus within tissue abscesses by MALDI IMS demonstrates a paucity of calprotectin signal. Analysis of the bacterial nidus.

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Fig. 7 Analysis of the bacterial nidus within tissue abscesses by MALDI IMS demonstrates a paucity of calprotectin signal. Analysis of the bacterial nidus within tissue abscesses by MALDI IMS demonstrates a paucity of calprotectin signal. (A and B) Two representative blockface images co-registered to MALDI IMS data for S100A8 (left), δ-hemolysin (middle), or both signals (right). White bar represents 1-mm scale. (C) Co-registration of MALDI IMS data for both S100A8 (blue) and δ-hemolysin (red) with blockface imaging across the entire infected kidney from one mouse infected with S. aureus 4 days before. Three representative images are shown. See also movie S10. James E. Cassat et al., Sci Transl Med 2018;10:eaan6361 Published by AAAS