Cystic fibrosis-related bone disease explored using a four step algorithm  Denise S.K. Brookes, Julie N. Briody, Craig F. Munns, Peter S.W. Davies, Rebecca J. Hill  Journal of Cystic Fibrosis  Volume 14, Issue 1, Pages 127-134 (January 2015) DOI: 10.1016/j.jcf.2014.07.011 Copyright © 2014 European Cystic Fibrosis Society. Terms and Conditions

Fig. 1 The guidelines of the 4 step algorithm interpretation for DXA. Firstly, the procedure assesses height and total body BMC for age. Thereafter, participants are classified as “low total body BMC considered for height” and are further assessed for LTM for height and total body BMC for LTM. Combining steps 3 and 4 concludes a possible biomechanical pathogenesis of a CF-related bone disease. Adapted from Hogler et al. [12] with permission. Journal of Cystic Fibrosis 2015 14, 127-134DOI: (10.1016/j.jcf.2014.07.011) Copyright © 2014 European Cystic Fibrosis Society. Terms and Conditions

Fig. 2 Total body Z-scores for each CF genotype category: (A) BMD as a group (homozygous: n=31; heterozygous: n=18; absent: n=4); (B) bone mineral content (BMC) as a group, and (C) BMC by sex (homozygous: n=19 F/12 M; heterozygous: n=13 F/5 M; absent: n=2 F/2 M). Mean±SD, *p<0.05. Journal of Cystic Fibrosis 2015 14, 127-134DOI: (10.1016/j.jcf.2014.07.011) Copyright © 2014 European Cystic Fibrosis Society. Terms and Conditions