Valerie W Rusch, MD, Ennapadam S Venkatraman, PhD

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Important prognostic factors in patients with malignant pleural mesothelioma, managed surgically Valerie W Rusch, MD, Ennapadam S Venkatraman, PhD The Annals of Thoracic Surgery Volume 68, Issue 5, Pages 1799-1804 (November 1999) DOI: 10.1016/S0003-4975(99)01038-3

Fig 1 Location of lymph node metastases by nodal station for right-sided (A) (n = 54) and left-sided (B) (n = 55) resections. The nomenclature for lymph node stations is that used for non-small cell lung cancer [10] and esophageal cancer [11]. Most patients who had lymph node metastases had more than one nodal station involved, so the number of metastatic sites exceeds the number of resections. The Annals of Thoracic Surgery 1999 68, 1799-1804DOI: (10.1016/S0003-4975(99)01038-3)

Fig 2 The relationship between tumor T status and overall survival by univariate analysis. When considered across all four categories, T status had a highly significant effect on survival (p < 0.01). The Annals of Thoracic Surgery 1999 68, 1799-1804DOI: (10.1016/S0003-4975(99)01038-3)

Fig 3 Univariate analysis of the relationship between the number of positive lymph nodes and overall survival. Patients who had four or more positive nodes had a significantly worse survival (p < 0.01). The Annals of Thoracic Surgery 1999 68, 1799-1804DOI: (10.1016/S0003-4975(99)01038-3)

Fig 4 Overall survival of all 231 patients by stage. When analyzed across all four categories, stage had a highly significant effect on survival (p < 0.01). The Annals of Thoracic Surgery 1999 68, 1799-1804DOI: (10.1016/S0003-4975(99)01038-3)

Fig 5 Comparison of the overall survival rates of patients who received adjuvant therapy versus those who did not, showing that adjuvant therapy was associated with a significantly better outcome (p < 0.01). The Annals of Thoracic Surgery 1999 68, 1799-1804DOI: (10.1016/S0003-4975(99)01038-3)

Fig 6 Overall survival analyzed according to the type of surgical procedure performed. There was no significant difference between patients who had all gross tumor removed via extrapleural pneumonectomy versus pleurectomy/decortication. The Annals of Thoracic Surgery 1999 68, 1799-1804DOI: (10.1016/S0003-4975(99)01038-3)