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Utility of Routine PET Imaging to Predict Response and Survival After Induction Therapy for Non-Small Cell Lung Cancer  Stephen A. Barnett, MBBS, Robert.

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Presentation on theme: "Utility of Routine PET Imaging to Predict Response and Survival After Induction Therapy for Non-Small Cell Lung Cancer  Stephen A. Barnett, MBBS, Robert."— Presentation transcript:

1 Utility of Routine PET Imaging to Predict Response and Survival After Induction Therapy for Non-Small Cell Lung Cancer  Stephen A. Barnett, MBBS, Robert J. Downey, MD, Junting Zheng, MS, Gabriel Plourde, BS, Ronglai Shen, PhD, Jamie Chaft, MD, Timothy Akhurst, MBBS, Bernard J. Park, MD, Valerie W. Rusch, MD  The Annals of Thoracic Surgery  Volume 101, Issue 3, Pages (March 2016) DOI: /j.athoracsur Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Overall survival by clinical stage before any treatment of non-small cell lung cancer. (CI = confidence interval; NA = not available.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Overall survival by pathologic stage after induction therapy and resection of non-small cell lung cancer. (CI = confidence interval; NA = not available; pCR = pathologic complete resection.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Overall survival by postinduction therapy maximal standardized uptake value (PostSUVmax) in the primary site of non-small cell lung cancer. (CI = confidence interval.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Overall survival by difference in maximal standardized uptake value (D) in the primary site of non-small cell lung cancer between preinduction and postinduction therapy positron emission tomography (D ≤ 0 is stable or decreased maximal standardized uptake value, D > 0 is increased). (CI = confidence interval; NA = not available.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Overall survival stratified by combination of pretreatment standardized uptake value (Pre SUV) and difference in maximal standardized uptake value (D) in the primary site of non-small cell lung cancer between preinduction and postinduction therapy positron emission tomography (D ≤ 0 is stable or decreased maximal standardized uptake value; D > 0 is increased). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

7 Fig 6 Overall survival by difference in maximal standardized uptake value in mediastinal lymph nodes involved with non-small cell lung cancer between preinduction and postinduction therapy positron emission tomography imaging (0 is stable or decreased maximal standardized uptake value, 1 is increased). (CI = confidence interval; NA = not available.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

8 Fig 7 Overall survival by difference in maximal standardized uptake value in mediastinal lymph nodes involved with non-small cell lung cancer between preinduction and postinduction therapy positron emission tomography imaging (0 is > 60% decrease in maximal standardized uptake value, 1 is < 60% decrease). (CI = confidence interval; NA = not available.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions


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