Kazunori Yoshida, MD, Satoshi Tobe, MD, Masahito Kawata, MD

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Acquired von Willebrand Disease Type IIA in Patients with Aortic Valve Stenosis Kazunori Yoshida, MD, Satoshi Tobe, MD, Masahito Kawata, MD The Annals of Thoracic Surgery Volume 81, Issue 3, Pages 1114-1116 (March 2006) DOI: 10.1016/j.athoracsur.2005.01.023 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Preoperative immunoblotting analysis. A deficit of von Willebrand factor large multimers is seen indicating type IIA von Willebrand syndrome. Black arrow shows the deficit zone of large multimers (L zone in the A). (A = patient before surgery; L = large multimers; M = middle multimers; N = control subject; S = small multimers; SS = very small multimers.) The Annals of Thoracic Surgery 2006 81, 1114-1116DOI: (10.1016/j.athoracsur.2005.01.023) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Postoperative immunoblotting analysis. Protein bands have normalized due to the increase in large multimers. (A = patient after surgery; L = large multimers; M = middle multimers; N = control subject; S = small multimers; SS = very small multimers.) The Annals of Thoracic Surgery 2006 81, 1114-1116DOI: (10.1016/j.athoracsur.2005.01.023) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions