Enlightenment on liver lanthanum exposure

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Enlightenment on liver lanthanum exposure S.J.P. Damment Kidney International Volume 70, Issue 7, Pages 1372-1373 (October 2006) DOI: 10.1038/sj.ki.5001636 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Long-term liver lanthanum exposure. Liver lanthanum concentrations in rats treated for 1 day, or 4, 12, 26, or 78 weeks with 1500–2000mg/kg lanthanum carbonate, 13–17 times the human dose of 3g/day of elemental lanthanum. Values are the median and 25th/75th percentiles, n=4–12 rats per time point. Data on file at Shire Pharmaceuticals Inc., in preparation for publication. Kidney International 2006 70, 1372-1373DOI: (10.1038/sj.ki.5001636) Copyright © 2006 International Society of Nephrology Terms and Conditions