Radiological findings on the development of ossification of the posterior longitudinal ligament (OPLL)-like ectopic ossification in famotidine-treated.

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Radiological findings on the development of ossification of the posterior longitudinal ligament (OPLL)-like ectopic ossification in famotidine-treated Enpp1ttw/ttw mice. Radiological findings on the development of ossification of the posterior longitudinal ligament (OPLL)-like ectopic ossification in famotidine-treated Enpp1ttw/ttw mice. (A) Representative micro-CT images of cervical spines of Enpp1ttw/ttw mice treated with or without famotidine. Famotidine was orally administered from 4 weeks of age. Micro-CT was performed at the indicated weeks of age. Bars=1 mm. (B) Quantitative analyses of OPLL-like ectopic ossification in Enpp1ttw/ttw mice treated with or without famotidine from 4 weeks of age. Four male and female mice were analysed in each group (n=8). X-axes indicate ages of mice. *p<0.05. Yujiro Maeda et al. RMD Open 2015;1:e000068 Copyright © BMJ Publishing Group & EULAR. All rights reserved.