Goal-directed haemodynamic therapy and gastrointestinal complications in major surgery: a meta-analysis of randomized controlled trials M.T. Giglio,

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Goal-directed haemodynamic therapy and gastrointestinal complications in major surgery: a meta-analysis of randomized controlled trials M.T. Giglio, M. Marucci, M. Testini, N. Brienza British Journal of Anaesthesia Volume 103, Issue 5, Pages 637-646 (November 2009) DOI: 10.1093/bja/aep279 Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

Fig 1 Flow chart summarizing the procedure of studies selection for the meta-analysis. British Journal of Anaesthesia 2009 103, 637-646DOI: (10.1093/bja/aep279) Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

Fig 2 Rates of postoperative major GI complications for each of the studies with ORs and 95% CIs. The studies were divided into two subgroups defined as high risk of bias and low risk of bias, according to the SIGN checklist (see text for details). The pooled OR and 95% CI are shown as the total. The size of the box at the point estimate of the OR gives a visual representation of the ‘weighting’ of the study. The diamond represents the point estimate of the pooled OR and the length of the diamond is proportional to the CI. British Journal of Anaesthesia 2009 103, 637-646DOI: (10.1093/bja/aep279) Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

Fig 3 Rates of postoperative minor GI complications for each of the studies included, with ORs and 95% CIs. The studies were divided into two subgroups defined as high risk of bias and low risk of bias, according to the SIGN checklist (see text for details). The pooled OR and 95% CI are shown as the total. The size of the box at the point estimate of the OR gives a visual representation of the ‘weighting’ of the study. The diamond represents the point estimate of the pooled OR and the length of the diamond is proportional to the CI. British Journal of Anaesthesia 2009 103, 637-646DOI: (10.1093/bja/aep279) Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

Fig 4 Rates of postoperative liver complications for each of the studies included, with ORs and 95% CIs. The pooled OR and 95% CI are shown as the total. The studies were divided into two subgroups defined as high risk of bias and low risk of bias, according to the SIGN checklist (see text for details). The pooled OR and 95% CI are shown as the total. The size of the box at the point estimate of the OR gives a visual representation of the ‘weighting’ of the study. The diamond represents the point estimate of the pooled OR and the length of the diamond is proportional to the CI. British Journal of Anaesthesia 2009 103, 637-646DOI: (10.1093/bja/aep279) Copyright © 2009 British Journal of Anaesthesia Terms and Conditions