Pharmacological prophylaxis in patients with recurrent gout, clinical tophi, or radiological erosiosns. * Contraindications to uricosuric drugs include:

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TXF Caveat on urate levels Serum uric acid level may be normal at the time of an acute attack. Normal level does not rule out gout. May be better.

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Pharmacological prophylaxis in patients with recurrent gout, clinical tophi, or radiological erosiosns. * Contraindications to uricosuric drugs include: known urate calculi, renal impairment (creatinine clearance <50 ml/min), 24 hour urinary urate > 800 mg, or previous intolerance. Pharmacological prophylaxis in patients with recurrent gout, clinical tophi, or radiological erosiosns. * Contraindications to uricosuric drugs include: known urate calculi, renal impairment (creatinine clearance <50 ml/min), 24 hour urinary urate > 800 mg, or previous intolerance. E Suresh Postgrad Med J 2005;81:572-579 Copyright © The Fellowship of Postgraduate Medicine. All rights reserved.