Editorial II British Journal of Anaesthesia

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Editorial II British Journal of Anaesthesia M.A. Gropper  British Journal of Anaesthesia  Volume 86, Issue 6, Pages 746-749 (June 2001) DOI: 10.1093/bja/86.6.746 Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 1 Early events leading to endothelial dysfunction in sepsis. An infectious agent triggers production of pro-inflammatory cytokines from leucocytes. These cytokines result in neutrophil–endothelial cell adhesion, activation of clotting and release of other inflammatory mediators. This endothelial injury eventually leads to multiple organ dysfunction syndrome. (Modified from Wheeler, New Engl J Med, 1994; 340: 207–14.) British Journal of Anaesthesia 2001 86, 746-749DOI: (10.1093/bja/86.6.746) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

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