Figure 1 Subject phenotypes and most common genotype in subjects enrolled in THAOS in continental Western Europe. Data ... Figure 1 Subject phenotypes.

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Presentation transcript:

Figure 1 Subject phenotypes and most common genotype in subjects enrolled in THAOS in continental Western Europe. Data ... Figure 1 Subject phenotypes and most common genotype in subjects enrolled in THAOS in continental Western Europe. Data are from all European countries included in THAOS. Shown are: the total number of subjects from each country in THAOS, the proportions of each phenotype, and the most common mutation in each country (with its percentage of all subjects in that country). Not shown are: Belgium, three subjects with cardiac + neurologic phenotype (genotypes: Val30Met, Glu54Leu, and Glu74Leu); and Cyprus, one subject with neurologic phenotype (genotype: Val30Met). Note that the most common form of ATTR amyloidosis in Germany and Italy was ATTRwt (41.6% and 34.2% of all subjects, respectively). Unless provided in the caption above, the following copyright applies to the content of this slide: Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Eur Heart J, ehz173, https://doi.org/10.1093/eurheartj/ehz173 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 2 A Kaplan–Meier survival curve by genotype for subject death Figure 2 A Kaplan–Meier survival curve by genotype for subject death. The 95% Hall–Wellner bands and Cox proportional ... Figure 2 A Kaplan–Meier survival curve by genotype for subject death. The 95% Hall–Wellner bands and Cox proportional hazards model are adjusted by age and sex (χ<sup>2</sup> log rank: P < 0.0001). Survival curves are from enrolment in THAOS. Unless provided in the caption above, the following copyright applies to the content of this slide: Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Eur Heart J, ehz173, https://doi.org/10.1093/eurheartj/ehz173 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 3 A Kaplan–Meier survival curve by phenotype for subject death Figure 3 A Kaplan–Meier survival curve by phenotype for subject death. The 95% Hall–Wellner bands and Cox proportional ... Figure 3 A Kaplan–Meier survival curve by phenotype for subject death. The 95% Hall–Wellner bands and Cox proportional hazards model are adjusted by age and sex (χ<sup>2</sup> log rank: P < 0.0001). Survival curves are from enrolment in THAOS. Unless provided in the caption above, the following copyright applies to the content of this slide: Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Eur Heart J, ehz173, https://doi.org/10.1093/eurheartj/ehz173 The content of this slide may be subject to copyright: please see the slide notes for details.