Tomoharu Akiba, MD*, Anton E. Becker, MD

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Disease of the left ventricle in pulmonary atresia with intact ventricular septum Tomoharu Akiba, MD*, Anton E. Becker, MD The Journal of Thoracic and Cardiovascular Surgery Volume 108, Issue 1, Pages 1-8 (July 1994) DOI: 10.5555/uri:pii:S0022522394702101 Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 1 Opened LV of a heart with pulmonary atresia with intact ventricular septum and a distinct subaortic septal bulge. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 1-8DOI: (10.5555/uri:pii:S0022522394702101) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 2 The opened left side of a heart with pulmonary atresia with intact ventricular septum (case 8). A, Small coronary sinus type atrial septal defect caused by a partially unroofed coronary sinus. The anterior leaflet of the mitral valve shows a small central cleft. The tendinous chords of the mitral valve are short and irregularly thickened with an abnormal branching pattern (see B). The LV wall shows marked hypertrophy at the basal part, exceeding twice the standard deviation of the mean value of age-matched normal hearts.B, Detail of the almost dysplastic tendinous chords arising from the posteromedial papillary muscle and insertion into the corresponding mitral valve leaflets. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 1-8DOI: (10.5555/uri:pii:S0022522394702101) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 3 Micrograph of the LV myocardium with extensive patchy replacement fibrosis. Picrosirius red stain, magnification ×35. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 1-8DOI: (10.5555/uri:pii:S0022522394702101) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 4 Micrographs of the LV myocardium stained with Picrosirius red for total collagen (case 8). A, Low-power magnification of myocardium shows fibrous tissue in perivascular location but no conspicuous increase of interstitial fibrous tissue (magnification × 35). B, Higher magnification of the same section shows a distinct endomysial (interfiber) collagen network. Microdensitophotometry showed a volume density of collagen twice the standard deviation of the mean value of age-matched normal hearts (magnification × 175). The Journal of Thoracic and Cardiovascular Surgery 1994 108, 1-8DOI: (10.5555/uri:pii:S0022522394702101) Copyright © 1994 Mosby, Inc. Terms and Conditions