XMCPDT Does Have Correct Type I Error Rates

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Presentation transcript:

XMCPDT Does Have Correct Type I Error Rates Jie Ding, Shili Lin  The American Journal of Human Genetics  Volume 82, Issue 2, Pages 528-530 (February 2008) DOI: 10.1016/j.ajhg.2007.11.011 Copyright © 2008 The American Society of Human Genetics Terms and Conditions

Figure 1 Comparisons of Type I Error Rates and Powers between X-APL and XMCPDT (A and B) Type I error and power, respectively, for the setting with three-children families with at least one affected. (C and D) Type I error and power, respectively, for the setting with OSUMS family structures. The horizontal dashed line in (A) and (C) marks the nominal level of type I error rate. A total of 12 models were considered: recessive models RA–RF and multiplicative models MA–MF.1 XMCPDTT and XMCPDTE are XMCPDT with true or estimated allele frequencies. The American Journal of Human Genetics 2008 82, 528-530DOI: (10.1016/j.ajhg.2007.11.011) Copyright © 2008 The American Society of Human Genetics Terms and Conditions