Use of an Adjustable Tourniquet to Reverse Cyanosis in the Newborn Pig

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Use of an Adjustable Tourniquet to Reverse Cyanosis in the Newborn Pig Kenneth G Warner, MD, Curtis C Quinn, MD, Richard D Klein, MD, Raymond J Connolly, PhD The Annals of Thoracic Surgery Volume 63, Issue 2, Pages 456-458 (February 1997) DOI: 10.1016/S0003-4975(96)00959-9

Fig. 1 The model viewed from a left thoracotomy. The adjustable tourniquet is placed around the anastomosis of the left atrial appendage (LA) to the main pulmonary artery (MPA). (Ao = aorta; LV = left ventricle.) The Annals of Thoracic Surgery 1997 63, 456-458DOI: (10.1016/S0003-4975(96)00959-9)

Fig. 2 Strip chart recording from a representative study. Left atrial pressure (LAp) and systemic blood pressure (SBP) did not change during the study. With opening (Open) of the tourniquet, the oxygen saturation (O2Sat) rose from 73% to 95%. Closing of the tourniquet (Close) again produced a saturation of 73%. The Annals of Thoracic Surgery 1997 63, 456-458DOI: (10.1016/S0003-4975(96)00959-9)

Fig. 3 Cumulative data for the eight studies. Systemic blood pressure (SBP), main pulmonary artery pressure (MPA), and left atrial pressure (LAP) did not change during the various phases of the experiment (p = not significant). The Annals of Thoracic Surgery 1997 63, 456-458DOI: (10.1016/S0003-4975(96)00959-9)

Fig. 4 Levels of systemic oxygenation for each study at baseline, with the tourniquet open, and with the tourniquet occluded. There was a significant fall in oxygenation after completion of the anastomosis (p < 0.001). Oxygen saturation with the shunt closed did not differ from baseline (p = not significant). The Annals of Thoracic Surgery 1997 63, 456-458DOI: (10.1016/S0003-4975(96)00959-9)