Postoperative Left Ventricular Mass Regression After Aortic Valve Replacement for Aortic Stenosis  Hiroshi Tomoeda, MD, Tomohiro Ueda, MD, Hideki Teshima,

Slides:



Advertisements
Similar presentations
Postoperative Left Ventricular Mass Regression After Aortic Valve Replacement for Aortic Stenosis  Hiroshi Tomoeda, MD, Tomohiro Ueda, MD, Hideki Teshima,
Advertisements

High Risk of Prosthetic Valve Endocarditis and Death After Valve Replacement Operations in Dialysis Patients  Danielle K. Farrington, MD, Patrick D. Kilgo,
Preliminary experience with the St
Survival Benefit of Aortic Valve Replacement in Patients With Severe Aortic Stenosis With Low Ejection Fraction And Low Gradient With Normal Ejection.
Intraoperative Pulmonary Artery Stenting: An Alternative Technique for the Management of Pulmonary Artery Stenosis  Fotios A. Mitropoulos, MD, PhD, Hillel.
Mitral Stenosis Reversed by Medical Treatment for Heart Failure
Coronary Artery Bypass for Heart Failure in Ischemic Cardiomyopathy: 17-Year Follow- Up  Marco Pocar, MD, PhD, Andrea Moneta, MD, Adalberto Grossi, MD,
Progressive Mitral Stenosis After MitraClip Implantation in a Patient With Systemic Inflammatory Disease  Mike Saji, MD, Gorav Ailawadi, MD, Dale E. Fowler,
Wenrui Ma, MD, Wei Zhang, MD, Wei Shi, MD, Ye Kong, MD, Xinyu Ma, MS 
Corey Adams, MD, Linrui Ray Guo, MD, Philip M
Mitral Stenosis Reversed by Medical Treatment for Heart Failure
Robert L. Smith, MD, Morley A. Herbert, PhD, Todd M
The Prevalence of Patient-Prosthesis Mismatch Can Be Reduced Using the Trifecta Aortic Prosthesis  Daniel Hernandez-Vaquero, MD, PhD, Rocio Diaz, MD,
Prosthetic Mitral Valve Replacement: Late Complications After Native Valve Preservation  Eduardo Esper, MD, Francis D Ferdinand, MD, Solomon Aronson,
Modified Starnes Procedure in a Neonate With Severe Tricuspid Regurgitation  Ashok Muralidaran, MD, Richard W. Kim, MD, Gary S. Kopf, MD, Nicholas P. Pietris,
Aortic Translocation for Repair of Transposition of the Great Arteries (S,D,L) With Ventricular Septal Defect and Pulmonic Stenosis  Justin G. Reeves,
Impact of the Improvement of Valve Area Achieved With Aortic Valve Replacement on the Regression of Left Ventricular Hypertrophy in Patients With Pure.
Surgical Removal and Replacement of Chronically Implanted Transcatheter Aortic Prostheses: How I Teach It  Abeel A. Mangi, MD, Mahesh Ramchandani, MD,
Surgical Management of Aortic Regurgitation Associated With Takayasu Arteritis and Other Forms of Aortitis  Osamu Adachi, MD, Yoshikatsu Saiki, MD, Junetsu.
Aortic Valve Replacement Improves Survival in Severe Aortic Stenosis Associated With Severe Pulmonary Hypertension  Ramdas G. Pai, MD, Padmini Varadarajan,
Enhanced Characterization of Ventricular Performance After Coarctation Repair in Neonates and Young Children  Liselotte M. Klitsie, MSc, Arno A.W. Roest,
Brian C. Gulack, MD, Ehsan Benrashid, MD, Robert D. B
Association of Thoracic Aorta Calcium Score With Left Ventricular Hypertrophy and Clinical Outcomes in Patients With Severe Aortic Stenosis After Aortic.
Transcatheter Aortic Valve Implantation Under Direct Visualization in Homograft Valve Endocarditis  Tarek Chami, MD, Guilherme Attizzani, MD, Benjamin.
Tomoaki Murakami, MD, PhD, Atsuhito Takeda, MD, PhD 
Which Patients Benefit From Stentless Aortic Valve Replacement?
Impact of Preoperative Symptoms on Postoperative Survival in Severe Aortic Stenosis: Implications for the Timing of Surgery  Sophie Piérard, MD, Christophe.
Mitroflow Aortic Bioprosthesis 5-Year Follow-Up: North American Prospective Multicenter Study  Federico M. Asch, MD, David Heimansohn, MD, Daniel Doyle,
The “Double-Valve” Sign in Acute Type A Aortic Dissection
Pulmonary Function Tests Overestimate Chronic Pulmonary Disease in Patients With Severe Aortic Stenosis  Mitchell J. Magee, MD, Morley A. Herbert, PhD,
Andreas Zierer, MD, Rochus K. Voeller, MD, Karen E
Acquired and Reversible von Willebrand Disease With High Shear Stress Aortic Valve Stenosis  Kazunori Yoshida, MD, Satoshi Tobe, MD, Masahito Kawata,
Aortic Elongation Induced Aortic Stenosis (AEAS)
Nihan Kayalar, MD, Hartzell V. Schaff, MD, Richard C
Tricuspid Reoperation After Left-Sided Rheumatic Valve Operations
Assessment of effective orifice area of prosthetic aortic valves with Doppler echocardiography: An in vivo and in vitro study  Odd Bech-Hanssen, MD, PhDa,
Impact of Age at Fontan Completion on Postoperative Hemodynamics and Long-Term Aerobic Exercise Capacity in Patients With Dominant Left Ventricle  Shuichi.
Expandable Valve for Pediatric Application Constructed From Human Venous Valved Conduit Within a Stent  Erin G. Roberts, MS, Luis Quinonez, MD, Breanna.
Kazunori Yoshida, MD, Satoshi Tobe, MD, Masahito Kawata, MD 
Freddy Vermeulen, MD, Ben Swinkels, MD, Wim Jan van Boven, MD 
Sixty Years After Tetralogy of Fallot Correction
Repair of a Duplicate Mitral Valve in a Patient With Ascending Aortic Aneurysm and Bicuspid Aortic Valve  Guy Jensen, MD, Thomas Smith, MD, Mona Flores,
Redo Aortic Valve Replacement in Children
Wall Stress and Geometry of the Thoracic Aorta in Patients With Aortic Valve Disease  Barry J. Doyle, PhD, Paul E. Norman, DS, Peter R. Hoskins, DSc, David.
Successful Use of Transvenous Atrial and Bifocal Left Ventricular Pacing in Ebstein’s Anomaly After Tricuspid Prosthetic Valve Surgery  J. Alberto Lopez,
Early Clinical and Hemodynamic Outcomes After Stented and Stentless Aortic Valve Replacement: Results From a Randomized Controlled Trial  Ayyaz Ali, MRCS,
Ayesha S. Bryant, MSPH, William L. Holman, MD, Navin C
Indexed Left Ventricular Dimensions Best Predict Survival After Aortic Valve Replacement in Patients With Aortic Valve Regurgitation  Morgan L. Brown,
Hemodynamics and early clinical performance of the St
Brian M. Cardis, MD, Derek A. Fyfe, MD, PhD, William T. Mahle, MD 
Effect of Prosthesis-Patient Mismatch on Long-Term Survival With Aortic Valve Replacement: Assessment to 15 Years  W.R. Eric Jamieson, MD, Jian Ye, MD,
Regression of hypertrophy after Carpentier-Edwards pericardial aortic valve replacement  Steven S Khan, MD, Robert J Siegel, MD, Michele A DeRobertis,
Patrick O. Myers, MD  The Annals of Thoracic Surgery 
Norwood Stage 1 With Surgical Ventricular Reconstruction and Mitral Valve Repair for Neonatal Idiopathic Left Ventricular Dilated Cardiomyopathy  Patrick.
Defining Patient-Prosthesis Mismatch and Its Effect on Survival in Patients With Impaired Ejection Fraction  David A. Cotoni, DO, Robert T. Palac, MD,
Invited Commentary The Annals of Thoracic Surgery
A Target for Perioperative Blood Pressure During Cardiac Operations
Reversibility of Cardiac Dysfunction After Valve Replacement in Elderly Patients With Severe Aortic Stenosis  Masafumi Natsuaki, MD, Tsuyoshi Itoh, MD,
Survival Benefit of Aortic Valve Replacement in Older Patients With Asymptomatic Chronic Severe Aortic Regurgitation  Rami Turk, MD, Padmini Varadarajan,
Late incidence and determinants of stroke after aortic and mitral valve replacement  Marc Ruel, MD, MPH, Roy G Masters, MD, Fraser D Rubens, MD, Pierre.
Pasquale Totaro, MD, Vincenzo Argano, MD 
Comparing Aortic Root Replacements: Porcine Bioroots Versus Pericardial Versus Mechanical Composite Roots: Hemodynamic and Ventricular Remodeling at Greater.
Influence of Prosthesis–Patient Mismatch on Diastolic Heart Failure After Aortic Valve Replacement  Shahab Nozohoor, MD, Johan Nilsson, MD, PhD, Carsten.
Dumbor L. Ngaage, MD, FRCS (C-Th), Michael E. Cowen, FRCS 
Bicuspid Aortic Valves and Dilatation of the Ascending Aorta: Reply
Small “Functional” Size after Mechanical Aortic Valve Replacement: No Risk in Young to Middle-Age Patients  Alfonso Penta de Peppo, MD, Jacob Zeitani,
Ebstein’s Anomaly of the Tricuspid Valve in Combination of Tetralogy of Fallot: Total Correction in Infancy  Chao-Han Lai, MD, Jing-Ming Wu, MD, Yu-Jen.
David H. Harpole, MD, Stanley A. Gall, MD, Walter G. Wolfe, MD, J
Surgical Reconstruction of Peripheral Pulmonary Arteries: Strategies, Outcomes, and New Classification  Abdulaziz Al-Khaldi, MD, MS, Omar Tamimi, MD 
Prosthetic Pulmonary Valve Stenosis: A Different Way to Solve the Problem  Thomas Schroeter, MD, Philipp Lurz, MD, PhD, Philipp Kiefer, MD, Mahmoud Wehbe,
Presentation transcript:

Postoperative Left Ventricular Mass Regression After Aortic Valve Replacement for Aortic Stenosis  Hiroshi Tomoeda, MD, Tomohiro Ueda, MD, Hideki Teshima, MD, Koichi Arinaga, MD, Keiichiro Tayama, MD, Shuji Fukunaga, MD, Shigeaki Aoyagi, MD  The Annals of Thoracic Surgery  Volume 89, Issue 3, Pages 745-750 (March 2010) DOI: 10.1016/j.athoracsur.2009.12.034 Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Preliminary study for adjustment of catheter pressure and Doppler echo pressure study. The relation between CPG and the pPG is described by the next formula; CP = 0.787 × pPG−2.25 (r2 = 0.68, p < 0.001). (CP = catheter pressure; pPG = peak pressure gradient measured by continuous-wave Doppler.) The Annals of Thoracic Surgery 2010 89, 745-750DOI: (10.1016/j.athoracsur.2009.12.034) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 The LV in systole was assumed to be a cone with a base diameter of Ds and a side wall radius of 1.85 Ds. (Ds = end-systolic diameter; LV = left ventricle.) The Annals of Thoracic Surgery 2010 89, 745-750DOI: (10.1016/j.athoracsur.2009.12.034) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Change in left ventricular mass index (LVMI). The LVMI significantly decreased within one year after operation, but no further regression was observed after that. (* = p < 0.01; ** = p < 0.05; Mp.o = months postoperative; Wp.o = weeks postoperative; Yp.o = years postoperative.) The Annals of Thoracic Surgery 2010 89, 745-750DOI: (10.1016/j.athoracsur.2009.12.034) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Correlation between the EOAI and LVMI six years after the operation. (Y = 117.7 + 15.6 X; r = 0.045; r2 = 0.002, p = 0.80.) (EOAI = effective orifice area index; LVMI = left ventricular mass index.) The Annals of Thoracic Surgery 2010 89, 745-750DOI: (10.1016/j.athoracsur.2009.12.034) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Correlation between sum of the pressure “SysBP + 0.8 × pPG” and left ventricular mass (LVM) six years after the operation (Y = −20.8 + 1.54 X, r = 0.48, r2 = 0.23, p < 0.004). SysBP indicates the lowest of three blood pressure readings obtained using a sphygmomanometer and pPG is the peak pressure data across the prosthesis obtained using continuous-wave Doppler. The Annals of Thoracic Surgery 2010 89, 745-750DOI: (10.1016/j.athoracsur.2009.12.034) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 When the patients were divided into two groups according to the sum of the pressure at the prosthetic valve orifice (H group: 150 mm Hg or more; L group: less than 150 mm Hg), the H group exhibited significantly higher left ventricular mass (LVM) compared with the L group. The Annals of Thoracic Surgery 2010 89, 745-750DOI: (10.1016/j.athoracsur.2009.12.034) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 7 Correlation between the factor of “EOA × (SysBP + 0.8 × pPG)” and LVM six years after the operation (Y = −43.5 + 1.17 X, r = 0.58, r2 = 0.34, p < 0.0004). (EOA = effective orifice area; LVM = left ventricular mass; pPG = peak pressure gradient; SysBP = lowest value of the systolic pressure.) The Annals of Thoracic Surgery 2010 89, 745-750DOI: (10.1016/j.athoracsur.2009.12.034) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 8 Correlation between the new index and the left ventricular mass (LVM) six years after the operation. The results indicate a strong correlation between the new index and the LVM (Y = 56.1 + 0.11 X, r = 0.82, r2 = 0.67, p < 0.0001.) The Annals of Thoracic Surgery 2010 89, 745-750DOI: (10.1016/j.athoracsur.2009.12.034) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions