Todd E. Golde, Lon S. Schneider, Edward H. Koo  Neuron 

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Anti-Aβ Therapeutics in Alzheimer's Disease: The Need for a Paradigm Shift  Todd E. Golde, Lon S. Schneider, Edward H. Koo  Neuron  Volume 69, Issue 2, Pages 203-213 (January 2011) DOI: 10.1016/j.neuron.2011.01.002 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 Preclinical AD The newly proposed staging of preclinical or prodromal AD reflects a cascade beginning with Aβ accumulation in the brain of clinically asymptomatic individuals and inexorably progressing to AD. Neuron 2011 69, 203-213DOI: (10.1016/j.neuron.2011.01.002) Copyright © 2011 Elsevier Inc. Terms and Conditions