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Alzheimer’s Disease Genetics: From the Bench to the Clinic

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Presentation on theme: "Alzheimer’s Disease Genetics: From the Bench to the Clinic"— Presentation transcript:

1 Alzheimer’s Disease Genetics: From the Bench to the Clinic
Celeste M. Karch, Carlos Cruchaga, Alison M. Goate  Neuron  Volume 83, Issue 1, Pages (July 2014) DOI: /j.neuron Copyright © 2014 Elsevier Inc. Terms and Conditions

2 Figure 1 Cell-Type Expression of Alzheimer’s Disease Risk Genes May Influence AD Pathogenesis The major cell types present in the brain are depicted. Genes are listed in the cell type in which they are most highly expressed (B. Barres, personal communication). GWAS loci that contain multiple genes were excluded from this figure, as it remains unclear which gene is responsible for the signal (CR1, BIN1, PICALM, HLA, SLC24A4, DSG2, ZCWPW1, CELF1, FERMT2, CASS4). Neuron  , 11-26DOI: ( /j.neuron ) Copyright © 2014 Elsevier Inc. Terms and Conditions

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