From Protein-RNA Predictions toward a Peptide-RNA Code

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Presentation transcript:

From Protein-RNA Predictions toward a Peptide-RNA Code Kristopher W. Brannan, Gene W. Yeo Molecular Cell Volume 64, Issue 3, Pages 437-438 (November 2016) DOI: 10.1016/j.molcel.2016.10.023 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 1 RBDmap and RBR-ID Are Two Methods that Utilize UV-Crosslinking of Protein to RNA Followed by Mass Spectrometry to Identify RNA Binding Domains Proteome-wide RBDmap uses serial interactome capture along with protease digestion steps to isolate RNA binding sites from crosslinked RBP-RNA complexes. RBR-ID discovers RBDs by depleting 4SU-mediated crosslinked peptides from mass spectra. Molecular Cell 2016 64, 437-438DOI: (10.1016/j.molcel.2016.10.023) Copyright © 2016 Elsevier Inc. Terms and Conditions