10.3 Regulation I. Controls A. Cell growth & division depend on protein signals & other environmental signals II. Checkpoints B. Feedback.

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10.3 Regulation I. Controls A. Cell growth & division depend on protein signals & other environmental signals II. Checkpoints B. Feedback signals at key checkpoints in the cell cycle can delay or trigger the next phase of the cell cycle. 1. Examples a. G1 checkpoint b. G2 checkpoint c. Mitosis checkpoint

III. Cancer A. def – group of severe & sometimes fatal diseases caused by uncontrolled cell growth B. Each year more than 1 million Americans are diagnosed with cancer C. Tumors form when a cell can no longer be controlled 1. it divides & produces more defective cells D. Benign Tumor 1. does not spread to other parts of the body & can be surgically removed E. Malignant Tumor 1. invades & spreads to nearby healthy tissues 2. Metastasis a. cancer cells breaking off & moving to other parts of the body to reproduce

F. Treatment 1. Chemotherapy - using drugs to cure 2. Radiation therapy 3. Surgery G. Prevention 1. Stay away from things that cause cancer. a. UV light, cigarettes, etc.