Is performing a scoping review useful after recent Cochrane review? TDH Smith1 A Akpan2 CE Lightbody3 M Gordon1 A Clegg3 C Watkins3 U Chauhan1 1School of Medicine, UCLan, 2Aintree University Hospital, 3Faculty of Health and Wellbeing, UCLan CHIME (Community Holistic Interventions for Multi-morbidity in older people: Evaluation of evidence) Reference lists: Cochrane2 97 Academy of Medical Sciences3 (ongoing trials) 19 Database searches 19/7/18: Medline 1335 EMBASE 107 Trial registers 27 Assessed for eligibility: 128 full-text articles 45 protocols Included in synthesis: 5 completed studies (from 5 papers) 3 ongoing studies 5 secondary studies or duplicates Excluded with reasons: 118 full-text articles 42 protocols 1412 records excluded based on title/abstract Journal hand searches: Ann Fam Med 0 BJGP 0 BMJ 0 JAMA 0 1585 records screened Background Purposes of scoping reviews1 To map extent, range and nature of research activity To check whether full systematic review worthwhile Summarise and demonstrate research findings to stakeholders Identify gaps in literature where more research needed Aims of CHIME Disseminate research findings to Liverpool CCG to aid local decision making Identify research gaps leading to NIHR Research for Patient Benefit (RfPB) funding bid } aiming for systematic review } facilitate other activities Methods Scoping methodology1 Aim of Poster To compare number, nature and reliability of evidence found using scoping search for CHIME, with those that could be obtained by using Cochrane review alone. Form research question Identify search strategy Select relevant studies Chart data Collate, summarise and report CHIME research question What is currently known from research about the effectiveness of community holistic interventions for older people with multimorbidity, what research is currently in progress, and what gaps in knowledge still exist? Differences in search approaches Difference CHIME search Cochrane search2 Gain/loss Search dates Included trials published since last Cochrane search Only included trials published up to 28 September 2015 +3 Community definition Occur in: primary care/minor injuries, patient’s usual residence, healthcare settings manned mainly or wholly by community-based practitioners Delivered by primary care professionals (i.e. treat all common conditions at all ages, ongoing relationship) +1 Holistic Addresses needs from at least 2 aspects of health: physical, mental, social, cultural Target at least 2 different health conditions -4 Multimorbidity 2 or more concordant or discordant physical/ mental illnesses 2 or more chronic conditions -1 Elderly Population/subgroup aged at least 60 Any age included -12 Completed studies 5 18 -13 Ongoing 3 (screened) 19 (not screened) -16 Results 5 published studies relevant to our population (i) being elderly (ii) having multimorbidity, and with an intervention that was (i) holistic in nature (ii) used in community setting 3 of these published since Cochrane review Only 1 of these newly published trials was listed as ongoing in Cochrane review 3 additional ongoing trials found likely to be relevant once complete Primary intervention method of the studies included in our review compared to Cochrane Conclusion Advantages of scoping review 1. Outperforms using old review in finding completed studies: Looking at included studies in Cochrane – 1 study Revisiting excluded studies too – 2 studies Adding ongoing studies – 3 studies Performing scoping review – 5 studies 2. Reviewing relevant ongoing studies better identifies gaps for future research Topic areas which no study used/using as primary intervention: Relevant Cochrane studies – 4 topic areas Adding completed studies from own search – 4 topic areas Adding ongoing studies – 3 topic areas Advantage of using Cochrane review Grades quality of evidence (for included studies only) Summary Performing a scoping review is worthwhile to identify needs for future research. However, there needs to be awareness that some included studies may be better quality than others. References 1. Arksey H, O'Malley L. Scoping studies: Towards a methodological framework. International Journal of Social Research Methodology: Theory & Practice 2005;8(1):19-32. 2. Smith SM, Wallace E, O’Dowd T, Fortin M. Interventions for improving outcomes in patients with multimorbidity in primary care and community settings. Cochrane Database of Systematic Reviews 2016;CD006560(3) 3. Academy of Medical Sciences, The. Multimorbidity: a priority for global health research. April 2018