Levocetirizine and Prednisone Are Not Superior to Levocetirizine Alone for the Treatment of Acute Urticaria: A Randomized Double-Blind Clinical Trial

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Presentation transcript:

Levocetirizine and Prednisone Are Not Superior to Levocetirizine Alone for the Treatment of Acute Urticaria: A Randomized Double-Blind Clinical Trial Caroline Barniol, MD, Emilie Dehours, MD, Jean Mallet, MD, Charles-Henri Houze-Cerfon, MD, Dominique Lauque, MD, Sandrine Charpentier, MD, PhD Annals of Emergency Medicine Volume 71, Issue 1, Pages 125-131.e1 (January 2018) DOI: 10.1016/j.annemergmed.2017.03.006 Copyright © 2017 American College of Emergency Physicians Terms and Conditions

Figure 1 Flow chart of the study. Annals of Emergency Medicine 2018 71, 125-131.e1DOI: (10.1016/j.annemergmed.2017.03.006) Copyright © 2017 American College of Emergency Physicians Terms and Conditions

Figure 2 Percentage and CIs of patients with an itch score of 0 of 10 in the prednisone and placebo groups. Annals of Emergency Medicine 2018 71, 125-131.e1DOI: (10.1016/j.annemergmed.2017.03.006) Copyright © 2017 American College of Emergency Physicians Terms and Conditions

Figure 3 Changes in each patient’s itch score from baseline to 2 days, contrasted between groups. For each treatment group, the day 0 itch score is sorted from highest (patient 1) to lowest (patient 50) and displayed along the gray line. For each patient, a line extends from that value to the day 2 value. The box plots show the overall group changes in itch score between both groups. Annals of Emergency Medicine 2018 71, 125-131.e1DOI: (10.1016/j.annemergmed.2017.03.006) Copyright © 2017 American College of Emergency Physicians Terms and Conditions

Figure E1 Changes in the percentage of total body surface area affected by urticaria (rash score) for each patient from baseline to day 2, contrasted between groups. For each treatment group, the day 0 rash score is sorted from highest (patient 1) to lowest (patient 50) and displayed along the gray line. For each patient, a line extends from that value to the day 2 value. The box plots show the overall group changes in rash score between both groups. Annals of Emergency Medicine 2018 71, 125-131.e1DOI: (10.1016/j.annemergmed.2017.03.006) Copyright © 2017 American College of Emergency Physicians Terms and Conditions