Prospective, Randomized, Double-Blind Study of High-Dose Aprotinin in Pediatric Cardiac Operations Michael J Davies, FRCS, Alison Allen, BScHons, Henry.

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Presentation transcript:

Prospective, Randomized, Double-Blind Study of High-Dose Aprotinin in Pediatric Cardiac Operations Michael J Davies, FRCS, Alison Allen, BScHons, Henry Kort, BS, Nihal A Weerasena, FRCS, Domenico Rocco, MD, Claire L Paul, BScHons, Beverley J Hunt, FRCP, Martin J Elliott, FRCS The Annals of Thoracic Surgery Volume 63, Issue 2, Pages 497-503 (February 1997) DOI: 10.1016/S0003-4975(96)01031-4

Fig. 1 Perioperative and 24-hour postoperative fibrin(ogen) degradation products (FDP) titers. (A = after anesthesia; B = before heparin administration; H = 4 hours postoperatively; I = 12 hours postoperatively; J = 24 hours postoperatively; ∗p < 0.02 for aprotinin group versus control group.) The Annals of Thoracic Surgery 1997 63, 497-503DOI: (10.1016/S0003-4975(96)01031-4)

Fig. 2 Perioperative and 24-hour postoperative β-thromboglobulin (bTG) levels. (A = after anesthesia; D = while on bypass; G = after administration of protamine; H = 4 hours postoperatively; ∗p = 0.03 for aprotinin group versus control group.) The Annals of Thoracic Surgery 1997 63, 497-503DOI: (10.1016/S0003-4975(96)01031-4)