High-speed visualization of disturbed pathlines in axial flow ventricular assist device under pulsatile conditions Fang Yang, PhD, Robert L. Kormos,

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Presentation transcript:

High-speed visualization of disturbed pathlines in axial flow ventricular assist device under pulsatile conditions Fang Yang, PhD, Robert L. Kormos, MD, James F. Antaki, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 150, Issue 4, Pages 938-944 (October 2015) DOI: 10.1016/j.jtcvs.2015.06.049 Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Transparent replica of the HeartMate II ventricular assist device (Thoratec, Pleasanton, Calif) and schematic of the visualization area. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 938-944DOI: (10.1016/j.jtcvs.2015.06.049) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Transparent replica of HeartMate II (HM II) ventricular assist device (Thoratec, Pleasanton, Calif) inserted into a simplified circulatory simulator, illuminated by a laser sheet. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 938-944DOI: (10.1016/j.jtcvs.2015.06.049) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Fluorescent particle pathlines within the upstream and downstream sections of the pump (inset) under steady conditions. A, At the nominal flow rate of 4.5 lpm the pathlines near the upstream bearing are generally aligned and coherent. B, Below 3.8 lpm, secondary flow disturbances become evident; shown here for 3.0 lpm. C and D, Pathlines in the aft stator are consistently chaotic for all flow rates studied (1.0-6.0 lpm). The Journal of Thoracic and Cardiovascular Surgery 2015 150, 938-944DOI: (10.1016/j.jtcvs.2015.06.049) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 A, Representative hemodynamic parameters for pulsatile condition, shown here for 4.5 lpm average flow. B, Same data plotted in terms of acceleration (dQ/dt) versus flow (Q) for 1 cardiac cycle, at 3 average hemodynamic conditions. The shaded region of panel II indicates conditions wherein disturbed flow was observed in the inlet stator region. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 938-944DOI: (10.1016/j.jtcvs.2015.06.049) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 5 Unsteady (pulsatile) hemodynamic conditions for average flow of 4.5 lpm. Left panel, Representative flow fields for the accelerating phase of the cardiac cycle (panel I in Figure 4). Right panel, Corresponding flow field for the decelerating phase (panel II in Figure 4). The Journal of Thoracic and Cardiovascular Surgery 2015 150, 938-944DOI: (10.1016/j.jtcvs.2015.06.049) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Path lines within axial flow ventricular assist device during the decelerating phase of the cardiac cycle. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 938-944DOI: (10.1016/j.jtcvs.2015.06.049) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions