343. Benchtop DNA Synthesizer: Oligo-Templated Polymerization (OTP) Molecular Therapy Volume 21, Pages S132-S133 (May 2013) DOI: 10.1016/S1525-0016(16)34678-0 Copyright © 2013 The American Society of Gene & Cell Therapy Terms and Conditions
Figure 1-OTP An oligo (Red) is selected from a comprehensive oligo array to anneal to the 3‘ of the growing chain (Green) such that the oligo's 5‘end protrudes and serves as a template for subsequent elongation. Denaturation then allows for a new cycle to begin. Molecular Therapy 2013 21, S132-S133DOI: (10.1016/S1525-0016(16)34678-0) Copyright © 2013 The American Society of Gene & Cell Therapy Terms and Conditions