1. Engineering the End: DNA Processing at Human Telomeres
Carolyn Price, Naduparambil K. Jacob 
Molecular Cell 
Volume 18, Issue 2, Pages (April 2005)
DOI: /j.molcel
Copyright © 2005 Elsevier Inc. Terms and Conditions

2. Figure 1
Techniques Used to Analyze the G and C Strand Termini of Human Telomeres
(A) Organization of the G strand overhang.
(B) C strand analysis. Adaptor oligonucleotides are hybridized to the G strand overhang; only those oligonucleotides that hybridize directly adjacent to the 5′ end will be ligated and amplified by PCR.
(C) G strand analysis. A 60 nt guide oligo is hybridized to the G overhang. This serves as a platform for hybridization and subsequent ligation of adaptor oligonucleotides. Black lines represent the chromosome terminus; blue bars, nontelomeric segment of adaptor oligonucleotide; red arrows, PCR primers
Molecular Cell  , DOI: ( /j.molcel )
Copyright © 2005 Elsevier Inc. Terms and Conditions