POPsicle for Fever! Cooling Down the Inflammasome

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POPsicle for Fever! Cooling Down the Inflammasome Kenichi Shimada, Timothy R. Crother, Moshe Arditi  Immunity  Volume 43, Issue 2, Pages 213-215 (August 2015) DOI: 10.1016/j.immuni.2015.08.004 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Mechanisms of Inflammasome Inhibition Left: POP1 binds to the PYD of ASC and prevents PYD-PYD interactions between ASC and NLRP3. Right: multiple inflammasome inhibitory mechanisms are shown, including POP1. Immunity 2015 43, 213-215DOI: (10.1016/j.immuni.2015.08.004) Copyright © 2015 Elsevier Inc. Terms and Conditions

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