Pulmonary Valve Replacement: A Comparison of Three Biological Valves

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Presentation transcript:

Pulmonary Valve Replacement: A Comparison of Three Biological Valves Andrew C. Fiore, MD, Mark Rodefeld, MD, Mark Turrentine, MD, Palaniswamy Vijay, PhD, Tyler Reynolds, MD, John Standeven, PhD, Kirstin Hill, Jamie Bost, Dustin Carpenter, MS, Courtney Tobin, MS, John W. Brown, MD The Annals of Thoracic Surgery Volume 85, Issue 5, Pages 1712-1718 (May 2008) DOI: 10.1016/j.athoracsur.2008.02.001 Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Pulmonary valve replacement (PVR) types at each institution per 5-year interval. The number of pulmonary valve implants each year stratified by group at both institutions: St. Louis University (SLU) porcine (black bar), SLU pericardial (diagonal hatched bars), and SLU homograft (checkered bars); and Indiana University (IU) porcine (horizontal hatched bars), IU pericardial (vertical striped bars), and IU homograft (plaid bars). (HO = homograft; PE = pericardial; PO = porcine.) The Annals of Thoracic Surgery 2008 85, 1712-1718DOI: (10.1016/j.athoracsur.2008.02.001) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 The change in pulmonary insufficiency (PI) before pulmonary valve replacement (solid bars) and at latest follow-up (open bars). PR grade: 1, mild; 2, moderate; 3, severe. (HO = homograft; PE = pericardial; PO = porcine.) The Annals of Thoracic Surgery 2008 85, 1712-1718DOI: (10.1016/j.athoracsur.2008.02.001) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 The change in right ventricular end-diastolic dimension (RVEDD) indexed to body surface area before pulmonary valve replacement (solid bars) and at latest follow-up (open bars). (HO = homograft; NS = not significant; PE = pericardial; PO = porcine; RVEDD = right ventricular end-diastolic dimension.) The Annals of Thoracic Surgery 2008 85, 1712-1718DOI: (10.1016/j.athoracsur.2008.02.001) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Quantitative comparison of the peak echocardiographic gradient (mm Hg) between the right ventricle and the main pulmonary artery before prosthetic pulmonary valve replacement (solid bars) and at latest follow-up (open bars). (HO = homograft; NS = not significant; PE = pericardial; PO = porcine.) The Annals of Thoracic Surgery 2008 85, 1712-1718DOI: (10.1016/j.athoracsur.2008.02.001) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Kaplan-Meier actuarial freedom from valve explantation in patients (Pts) who underwent initial pulmonary valve replacement for chronic pulmonary insufficiency. (HO = homograft; PE = pericardial; PO = porcine.) The Annals of Thoracic Surgery 2008 85, 1712-1718DOI: (10.1016/j.athoracsur.2008.02.001) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions