Advances in Multiple Myeloma: Data Highlights and Analysis from the 2015 Hematology/Oncology Conferences.

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Presentation transcript:

Advances in Multiple Myeloma: Data Highlights and Analysis from the 2015 Hematology/Oncology Conferences

Program Goals

Newly Diagnosed Multiple Myeloma

Current Approaches for Newly Diagnosed Multiple Myeloma (MM)

Importance of Fitness in Older Patients With MM

Future Directions in Treatment of Newly Diagnosed MM

Relapsed/Refractory Multiple Myeloma (R/R MM)

PANORAMA 1 Bortezomib/Dexamethasone ± Panobinostat

ASPIRE Carfilzomib, Lenalidomide, Dexamethasone (KRd) vs Len/Dex (Rd)

ENDEAVOR Carfilzomib/Dexamethasone (Kd) vs Bortezomib/Dexamethasone (Vd) in Patients With 1-3 Prior Lines of Therapy

Monoclonal Antibodies in Multiple Myeloma

ELOQUENT-2 Len/Dex ± Elotuzumab (anti-SLAMF7) in Relapsed/Refractory MM

SIRIUS Phase 2 Study of Daratumumab (anti-CD38) in Heavily Pretreated MM

Monoclonal Antibodies in MM Future Directions

New Targets in Multiple Myeloma

Novel Proteasome Inhibitors in Development

Novel Targeted Therapy Approaches in MM

Novel Approaches to MM Therapy

Biological Profiling of Multiple Myeloma

Current Role of Cytogenetics Prognostic Information

Measuring MRD in MM

MM is Heterogeneous in its Genetics

Summary Multiple Myeloma in 2015

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