Pathergy response to skin prick testing

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Presentation transcript:

Pathergy response to skin prick testing Thomas L. Johnson, USAF, MC, MD, Patrick E. McCleskey, USAF, MC, MD, Melinda Rathkopf, USAF, MC, MD, Jeffrey J. Meffert, MD, Larry L. Hagan, USAF, MC, MD  Journal of Allergy and Clinical Immunology  Volume 119, Issue 5, Pages 1270-1272 (May 2007) DOI: 10.1016/j.jaci.2007.01.033 Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Pathergy response on the back in the pattern of skin prick testing (A) with close-up (B). Journal of Allergy and Clinical Immunology 2007 119, 1270-1272DOI: (10.1016/j.jaci.2007.01.033) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Punch biopsy of pathergy lesion at ×20 magnification, stained with hematoxylin and eosin (A), CD8 immunostain (B), and CD4 immunostain (C). D, Punch biopsy 24 hours after intradermal injection of histamine into forearm, stained with hematoxylin and eosin, ×40. Journal of Allergy and Clinical Immunology 2007 119, 1270-1272DOI: (10.1016/j.jaci.2007.01.033) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions