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Apixaban Causing Leukocytoclastic Vasculitis

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Presentation on theme: "Apixaban Causing Leukocytoclastic Vasculitis"— Presentation transcript:

1 Apixaban Causing Leukocytoclastic Vasculitis
Usama Bin Nasir, MD, Aswini Kumar, MD, Arti Easwar, MD  The Journal of Allergy and Clinical Immunology: In Practice  Volume 6, Issue 5, Pages (September 2018) DOI: /j.jaip Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Figure 1 Left lower foot showing LCV lesions in different phase of healing. The Journal of Allergy and Clinical Immunology: In Practice 2018 6, DOI: ( /j.jaip ) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Figure 2 A, Left lower limb, punch biopsy (hematoxylin-eosin [H&E]; original magnification ×10). B, Left lower limb, punch biopsy (H&E; original magnification ×20). C, Left lower limb, punch biopsy (H&E; original magnification ×40). The above figures show H&E sections at 10× (Figure 2, A), 20× (Figure 2, B), and 40× (Figure 2, C) magnification of a punch biopsy of the left lower limb showing features of leukocytoclastic LCV. There is a perivascular neutrophilic infiltrate around the superficial vascular plexus. Fibrinoid necrosis of the vessel wall (arrow), extravasated erythrocytes, and neutrophilic nuclear debris are also evident. The Journal of Allergy and Clinical Immunology: In Practice 2018 6, DOI: ( /j.jaip ) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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