Naïve B cells (CD19+CD27-), memory B cells (CD19+CD27+) and plasmablasts (PB CD27++) levels in patients with systemic sclerosis. Indicated points resemble.

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Naïve B cells (CD19+CD27-), memory B cells (CD19+CD27+) and plasmablasts (PB CD27++) levels in patients with systemic sclerosis. Indicated points resemble medians; Rituximab: T0, n= 8; T3 n=8; T6 n=7; T12 n=6; T24 n=4; Placebo: T0, n=8; T3, n=8; T6 n=8; T12 n=7; T24 n=7. Total events are defined as the number of detected cells by the flow cytometer. B cell depletion after rituximab treatment is seen in all B cell subsets. Naïve B cells (CD19+CD27-), memory B cells (CD19+CD27+) and plasmablasts (PB CD27++) levels in patients with systemic sclerosis. Indicated points resemble medians; Rituximab: T0, n= 8; T3 n=8; T6 n=7; T12 n=6; T24 n=4; Placebo: T0, n=8; T3, n=8; T6 n=8; T12 n=7; T24 n=7. Total events are defined as the number of detected cells by the flow cytometer. B cell depletion after rituximab treatment is seen in all B cell subsets. Maaike Boonstra et al. RMD Open 2017;3:e000384 Copyright © BMJ Publishing Group & EULAR. All rights reserved.