1. NRDC and TNF-α increase in synovial fluid from patients with RA
NRDC and TNF-α increase in synovial fluid from patients with RA. (A) NRDC concentration in synovial fluid from OA (n=17) and RA (n=20) patients. **p<0.01, Welch’s t-test.
NRDC and TNF-α increase in synovial fluid from patients with RA. (A) NRDC concentration in synovial fluid from OA (n=17) and RA (n=20) patients. **p<0.01, Welch’s t-test. (B) TNF-α concentration in synovial fluid from OA and RA patients. **p<0.01, Welch’s t-test. (C) NRDC in synovial fluid has a tendency of positive correlation with TNF-α in RA patients. Solid line, approximate line; broken line, 95% CI. r=0.44, p=0.054, Spearman’s rank correlation test. (D) NRDC in synovial fluid is significantly correlated with CRP in RA patients. Solid line, approximate line; broken line, 95% CI. r=0.50, p<0.05, Spearman’s rank correlation test. 
Takayuki Fujii et al. RMD Open 2017;3:e000436
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