Kusum Lata, Rajesh Janardhanan Journal of Indian College of Cardiology

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Presentation transcript:

A rare case of SVC syndrome: Accurate diagnosis by multi-modality imaging Kusum Lata, Rajesh Janardhanan Journal of Indian College of Cardiology Volume 4, Issue 2, Pages 119-121 (June 2014) DOI: 10.1016/j.jicc.2014.03.005 Copyright © 2014 Terms and Conditions

Fig. 1 Chest X-Ray showing a widened mediastinum. Journal of Indian College of Cardiology 2014 4, 119-121DOI: (10.1016/j.jicc.2014.03.005) Copyright © 2014 Terms and Conditions

Fig. 2 Chest CT, a large solid mass in the right hemithorax filling the right atrium. Journal of Indian College of Cardiology 2014 4, 119-121DOI: (10.1016/j.jicc.2014.03.005) Copyright © 2014 Terms and Conditions

Fig. 3 Transthoracic echocardiogram, bulky mass in the right atrium. Journal of Indian College of Cardiology 2014 4, 119-121DOI: (10.1016/j.jicc.2014.03.005) Copyright © 2014 Terms and Conditions

Fig. 4 Cardiac MRI depicts mass infiltrating the superior vena cava and extending into the right atrium. Journal of Indian College of Cardiology 2014 4, 119-121DOI: (10.1016/j.jicc.2014.03.005) Copyright © 2014 Terms and Conditions

Fig. 5 Cardiac MRI showing the tumor mass filling the right atrium. Journal of Indian College of Cardiology 2014 4, 119-121DOI: (10.1016/j.jicc.2014.03.005) Copyright © 2014 Terms and Conditions

Fig. 6 Histologic examination of the mediastinal mass reveals a diffuse proliferation of large atypical appearing CD20 and Pax 5 positive cells, indicating that these are B cells. The neoplastic cells are CD 10 negative and express BCL6 and MUM1 consistent with a post-germinal center phenotype. ALK 1 staining is negative. The morphologic features and immunophenotype are consistent with a diffuse large B cell lymphoma, post-germinal center B cell phenotype. Journal of Indian College of Cardiology 2014 4, 119-121DOI: (10.1016/j.jicc.2014.03.005) Copyright © 2014 Terms and Conditions