Successful Treatment of Severe Acute Intestinal Graft-versus-Host Resistant to Systemic and Topical Steroids with Alemtuzumab  Marc Schnitzler, Jens Hasskarl,

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Presentation transcript:

Successful Treatment of Severe Acute Intestinal Graft-versus-Host Resistant to Systemic and Topical Steroids with Alemtuzumab  Marc Schnitzler, Jens Hasskarl, Matthias Egger, Hartmut Bertz, Jürgen Finke  Biology of Blood and Marrow Transplantation  Volume 15, Issue 8, Pages 910-918 (August 2009) DOI: 10.1016/j.bbmt.2009.04.002 Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Survival and nonrelapse mortality of patients with severe steroid-refractory GVHD after first treatment with alemtuzumab. (A) Survival function depending on response to alemtuzumab. The dotted line represents survival of patients responding to alemtuzumab; the solid line, survival of patients not responding to alemtuzumab; the black line, survival of all patients. Censored subjects are indicated. (B) Fractional risk of death in patients with or without relapse of underlying disease. The dashed line represents relapse mortality after treatment with alemtuzumab; the dotted line, nonrelapse mortality after treatment with alemtuzumab; the solid line, risk of death for all patients. Censored subjects are marked. Biology of Blood and Marrow Transplantation 2009 15, 910-918DOI: (10.1016/j.bbmt.2009.04.002) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions