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Total Body Irradiation–Based Myeloablative Haploidentical Stem Cell Transplantation Is a Safe and Effective Alternative to Unrelated Donor Transplantation.

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Presentation on theme: "Total Body Irradiation–Based Myeloablative Haploidentical Stem Cell Transplantation Is a Safe and Effective Alternative to Unrelated Donor Transplantation."— Presentation transcript:

1 Total Body Irradiation–Based Myeloablative Haploidentical Stem Cell Transplantation Is a Safe and Effective Alternative to Unrelated Donor Transplantation in Patients Without Matched Sibling Donors  Scott R. Solomon, Connie A. Sizemore, Melissa Sanacore, Xu Zhang, Stacey Brown, H. Kent Holland, Lawrence E. Morris, Asad Bashey  Biology of Blood and Marrow Transplantation  Volume 21, Issue 7, Pages (July 2015) DOI: /j.bbmt Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Cumulative incidence of (A) acute GVHD and (B) chronic GVHD.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Cumulative incidence of (A) hemorrhagic cystitis of any grade and (B) grade ≥ 3 hemorrhagic cystitis. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Kaplan-Meier analysis of overall survival, disease-free survival, nonrelapse mortality and relapse for (A) all patients, (B) patients with low/intermediate disease risk, and (C) patients with high/very high disease risk. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Kaplan-Meier analysis of disease-free survival, comparing recipients of myeloablative haplo-HSCT versus myeloablative MUD transplants for (A) all patients, (B) patients with low/intermediate disease risk, and (C) patients with high/very high disease risk. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

6 Figure 5 Cumulative incidence of (A) grade II to IV acute GVHD, and (B) moderate-to-severe chronic GVHD, comparing recipients of myeloablative haplo-HSCT versus myeloablative MUD transplantation. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

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