Enzyme Action Enzymes … proteins with catalytic function

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Presentation transcript:

Enzyme Action Enzymes … proteins with catalytic function … possess 1O, 2O, 3O and 4O structure … perform a variety of reactions e.g., hydrolysis, hydroxylation, oxidation, reduction, transfer of groups … … increase the rate of reaction (up to 1017-fold) MEDC 527 Fall 2008

Enzyme Action Three dimensional structure of an enzyme MEDC 527 Fall 2008

Enzyme Action Catalytic Triad Catalytic Triad Chymotrypsin Acetylcholine Esterase MEDC 527 Fall 2008

Chemical Mechanism of Enzyme Action MEDC 527 Fall 2008

Michaelis – Menten Kinetics and Enzyme Inhibition MEDC 527 Fall 2008