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Enzymes Reaction Part II

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Presentation on theme: "Enzymes Reaction Part II"— Presentation transcript:

1 Enzymes Reaction Part II
PSSH Enzyme Kinetics

2 Active Intermediates/Free Radicals

3 Active Intermediates/Free Radicals

4 Active Intermediates/Free Radicals
Mechanism:

5 Active Intermediates/Free Radicals
Mechanism:

6 Active Intermediates/Free Radicals
Mechanism:

7 Active Intermediates/Free Radicals
Mechanism:

8 Pseudo Steady State Hypothesis (PSSH)
A* is an active intermediate that is highly reactive. It disappears as fast as it is formed.

9 Pseudo Steady State Hypothesis (PSSH)
A* is an active intermediate that is highly reactive. It disappears as fast as it is formed.

10 Pseudo Steady State Hypothesis (PSSH)
A* is an active intermediate that is highly reactive. It disappears as fast as it is formed.

11 Pseudo Steady State Hypothesis (PSSH)
A* is an active intermediate that is highly reactive. It disappears as fast as it is formed.

12 Pseudo Steady State Hypothesis (PSSH)
A* is an active intermediate that is highly reactive. It disappears as fast as it is formed.

13 Pseudo Steady State Hypothesis (PSSH)
A* is an active intermediate that is highly reactive. It disappears as fast as it is formed.

14 Pseudo Steady State Hypothesis (PSSH)

15 Enzymes: Michaelis-Menten Kinetics

16 Enzymes: Michaelis-Menten Kinetics

17 Enzymes: Michaelis-Menten Kinetics

18 Urea Decomposition A given enzyme can only catalyze only one reaction.  Urea is decomposed by the enzyme urease, as shown below.

19 Urea Decomposition A given enzyme can only catalyze only one reaction.  Urea is decomposed by the enzyme urease, as shown below.

20 Urea Decomposition A given enzyme can only catalyze only one reaction.  Urea is decomposed by the enzyme urease, as shown below. Rate Laws:

21 Urea Decomposition A given enzyme can only catalyze only one reaction.  Urea is decomposed by the enzyme urease, as shown below. Rate Laws:

22 Urea Decomposition A given enzyme can only catalyze only one reaction.  Urea is decomposed by the enzyme urease, as shown below. Rate Laws: If

23 Urea Decomposition

24 Urea Decomposition

25 Urea Decomposition

26 Urea Decomposition

27 Urea Decomposition VMAX rP Km S

28 Urea Decomposition

29 Types of Enzyme Inhibition

30 Types of Enzyme Inhibition

31 Types of Enzyme Inhibition

32 Types of Enzyme Inhibition

33 Types of Enzyme Inhibition


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