Splitting Schizophrenia: Periodic Catatonia–Susceptibility Locus on Chromosome 15q15 Gerald Stöber, Kathrin Saar, Franz Rüschendorf, Jobst Meyer, Gudrun.

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Splitting Schizophrenia: Periodic Catatonia–Susceptibility Locus on Chromosome 15q15 Gerald Stöber, Kathrin Saar, Franz Rüschendorf, Jobst Meyer, Gudrun Nürnberg, Susanne Jatzke, Ernst Franzek, André Reis, Klaus- Peter Lesch, Thomas F. Wienker, Helmut Beckmann The American Journal of Human Genetics Volume 67, Issue 5, Pages 1201-1207 (November 2000) DOI: 10.1016/S0002-9297(07)62950-4 Copyright © 2000 The American Society of Human Genetics Terms and Conditions

Figure 1 Genomewide linkage scan for periodic catatonia–susceptibility loci. The multipoint nonparametric Zlr scores (GH-PLUS) are computed for the whole panel of 12 families. The X-axis represents the genetic location on the 22 autosomes; chromosomes are arranged, by number, from pter to qter, on a linear scale (in cM); and the Y-axis represents the nonparametric Zlr score. Evidence for linkage was obtained at chromosome 15q15 with Zlr = 4.05 (P=2.6×10−5). A second susceptibility locus is on chromosome 22q13 (Zlr=2.92; P=1.8×10−3). The American Journal of Human Genetics 2000 67, 1201-1207DOI: (10.1016/S0002-9297(07)62950-4) Copyright © 2000 The American Society of Human Genetics Terms and Conditions